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Adderall vs Vyvanse (The Real Deal)

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James Oskey (23 days ago)
One of Hitler's favorite hobbies .. among other things.
Black Wallstreet (26 days ago)
How do you fix the permanent side affects?
all amphetamine is dangerous, they wear you out and make you aggressive and angry over time, if you don't know you've taken them (spiked) the effects are worse as your not able to consciously control what's happening to you. people who spike other people think its funny, it isn't, don't do it as the consequences can be very bad especially if the spiked person has been drinking alcohol.
Pink Rey (1 month ago)
you taught this extremely well
T smith (1 month ago)
Dylan Banocy (1 month ago)
this guy is fucking Brilliant. thank you
Chelsea Hackfeld (2 months ago)
Can someone please explain to me the difference with Vyvanse and Adderall and meth and speed? I always get into this argument and i am tired of getting called a meth head!
TheNFL4ever (2 months ago)
Thanks for this beautiful video,my questione is,are there sode effects from vyvanse?please help me
Andrew Shockey (3 months ago)
Just common sense,I take vyvanse. Helps with TBI...
Shannon H (3 months ago)
This kid is so cute.
Izabella Tönnhed (4 months ago)
Yu are Sexy💞💞
Joey Zee (4 months ago)
ok, so now that adderall IR as well as XR is available in generic forms, WHY do doctors still prescribe 'mixed amphetamine salts' aka generic adderall when dextroamphetamine (dexedrine) is really the only useful molecule? Would it be reasonable to bring this up to my doctor and request just generic dextroamphetime? Also, I recently came across another ADHD drug called Evekeo™ which is 50/50 levoamphetamine/dextroamphetamine. Seems like they're reinventing the wheel. What do you think???
DaveBAWZ (4 months ago)
hey whats up
Inthe Garbage (4 months ago)
I think you are wrong. The reason for the added part is to aid slow and stable release because of the theraputic purpuse not having to konstantly adding more and ceeping a stable low amount in the system longer making it much safer and less addictive and only ceeping the theraputic effects!
Angel Ventura (5 months ago)
Very informative. Gracias!
Kathleen Kennedy (5 months ago)
Moron is high
Kathleen Kennedy (5 months ago)
Shut up all those drugs are meth monacule or not
CrosstownCash (8 months ago)
My doc put me on vyvanse cause adder all made me so anxious and paranoid and now I know why she did that. I always thought these drugs were all the same. I don't feel no physical side effects like I use too and no wonder I can't use vyvanse in the gym also. Aderall worked like a charm there . Thanks for this info . Helped a lot
Val D (8 months ago)
Thanks you so much that was very helpful
Tobi McLaughlin (8 months ago)
Why didn’t they just renew their patents?
Ian McCracken (8 months ago)
Vyvanse is alot smother through the day than Adderall
brandon mckay (8 months ago)
great vid, very well explained!
youssef elbadry (8 months ago)
I get my vyvanse from 6$ cause I have benefits
Yoshi Mungus (9 months ago)
This video was quite informative up to the point until he starts to wear a tin-hat claiming that including a rate-limiting enzymatic cleavage to an L-lysine portion of a molecule was just for a patent, or that including a mixture of the two salts is a bad idea (i.e. Adderall's 3:1 ratio) concluding that drugs containing only Dextroamphetamine is the most useful. In this study, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666194/, it was proven in rats that l-amphetamine significantly enhanced and prolonged the efflux of dopamine in the striatum produced by d-amphetamine, leading to a synergistic effect v.s. tin-foil hat patenting. Both isomers were also capable of increasing striatal dopamine efflux by >5000% of baseline values, though it is agreed that d-amphetamine is more potent. However, I also found it funny how this study was "support funded" by Shire themselves, so I myself put on my tin-foil hat and dived through their references (you may have heard of a reference, but it is something you did not list in this video): https://pdfs.semanticscholar.org/a231/0e705013f26dbe2380525e8e8f475623e6d5.pdf. Now Arnold's premise was to that the two isomers have different effects on aggression and hyperkineses. Though the paper does end with yet another hypothesis, it does go over points where l-amphetamine did show benefits toward patients subjected to hyperkinetic syndrome, aggression, and hostility by both isomers via a dopaminergic mechanism, while those with anxiety or over activity could benefit solely from d-amphetamine. This is much more conclusive than the tin-foil hat that you put on about America's Patenting System™.
What is difrent betwen concerta or adderal or modafinal
Dan Johnson (9 months ago)
Adderall/l-amphetamine really helps my mood for some reason while vyvanse/d-amp is solely a focusing tool. Adderall fully cured my bipolar problem for ~8 months'ish so far. Amazing time we live in.
Emad Alnakhli (10 months ago)
The bottom line is ,vyvanse is much better. Thanks 🙏🏽
Make a video on DMAA and how it compares in effects and in molecular structure to Adderall, Vyvanse(dextroamphetamine), and Ritalin. Dmaa is or was a big thing in pre workout supplements. Im curious if its effects on cognition are similar to dextroamphetamine or adderall cuz it can still be gotten online for cheap wit no script as a "reaearch chemical" like $15 for 1 gram
helzefeld (11 months ago)
Thank you for the explanation. I actually learned a lot. I wanted to know if I should switch from Adderall to Vyvanse for my ADD and it looks like Adderall generic is just as fine.
aghmnk mj (11 months ago)
Wow, thanks for the clear explanation. I just got prescribed Vyvanse price is out the ass expensive however, my insurance covered cost but they didn't want to my doctor had to give them an explanation as to why I need vyvanse instead of addreal because they didnt want to pay for it. eneded up getting approved my dr had to throw the word bieng eat disorder and adhd to get it approved. lol toatally ridculous
Leah Michaels (11 months ago)
excellent video....good info and actually explains the business reasons behind these drugs....and that is really what drives it
J. Fomoiri (1 year ago)
having experience with the adhd-meds, including ritalin/concerta, i prefer vyvanse. i like the slower gradual onset. adderall was good but due to the various salts and metabolism rate i found the onset a bit jerky. dexedrine was fast but it also has a lot more abuse potential (sniffing & injection) which is my understanding as to why it's not as prescribed. ritalin was too short lived whereas concerta wasn't, although with that i was clenching/grinding my teeth. btw - i'm coming at this from a therapeutic perspective, not someone whose used these recreationally. fortunately where i am in canada i don't pay a cent for any of these :D
underscore boogiedown (1 year ago)
" ..Diffricult "
Creeping Normalcy (1 year ago)
Vyvanse is a marketing hoax. It's not extended release by any means. The most accurate way to describe it is delayed release. It takes about 2 hours longer to give any effect compared with regular (instant release) dextroamphetamine, but after that they are indistinguishable and duration of effects is identical - except that Vyvanse will have an total effect duration that is ~2 hours delayed compared to a single dose of regular dextroamphetamine. One more thing: levoamphetamine adds an physically energizing dimension to the otherwise mellow dextro isomer, which some of us sorely need. PEACE!
Creeping Normalcy (1 year ago)
Len M. Well one dose of instant release d-amphetamine will be effective for about 4-6 hours in most people, hence they are usually dosed 2 to 4 times a day. Then you look at the plasma reality: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594082/figure/F1/
Len M. (1 year ago)
Creeping Normalcy That’s how Extended Release Medications work, they either have a Coating or an extra step metabolizing them. Patches work by calculating the area of the skin the Patch will effect times the absorption rate of the drug.
sped monie (1 year ago)
Is this sons of Apollo ?
Dmcy (1 year ago)
Smart man! Thank you
El Bat (1 year ago)
Adderall is way better
Chris Phaneuf (1 year ago)
Explaining 30 seconds worth of information in 15 minutes... I love speed.
butterfly longhair (1 year ago)
really well explained thank you it hroped a mil
Jennifer Gagnon (1 year ago)
thank you for the talk! been searching for answers,,,,you explained it perfect......thanks!!!!
Alexis Thalia (1 year ago)
geez so attracive
Bill W (1 year ago)
I LOVE this explanation is WAYyy more clear than any other reviews. Thank you Sir!
Youtube Britney (1 year ago)
Actual content starts at minute 12:00. You're welcome.
blitch clap4me (1 year ago)
Really informative and easy and calmly explained! You're doing a good job at this. I wish you were my chemistry teacher or doctor.
Brandon Bright (1 year ago)
Can you make a video about lexapro and other popular antidepressants
Mr Schmeltz (1 year ago)
Alex Martinez (1 year ago)
Great job explaining the differences between this two popular drugs
vanpride64 (1 year ago)
worst teacher ever, he must be a professor at a college. shut up, tell me the difference between the two..
contranym_ (1 year ago)
thank you for helping me school my doctors who swear up and down there is no difference whatsoever
Robert Elliott (1 year ago)
I need adderrall to keep up with this dude
Dexter (1 year ago)
Finally a guy who knows his shit
matt rossall (1 year ago)
so I've been on Vyvanse since 2012 and it's now 2017 and I really want to change things up and I did the other day! got prescribed dexedrine 30mg IR. but supposedly the pharmacy I'm at won't support it or maybe there is an insurance problem.... Any tips?
Off-Grid Optimist (1 year ago)
site your references please...
Worldlink Center TV (1 year ago)
Pure dex feels so much cleaner and refreshing than addy.
EL CAPITAN (1 year ago)
Thank you
Rafael Conte (1 year ago)
You are great for those of us who do understand and deal with theses substances. Please keep up your good work. Thanks.
fernando contreras (1 year ago)
modafinil is the most overrated medication I've ever tried is nothing compared to these people hyping this way to much making videos on how modafinil will change your life this in that it's sad how they praise a medication that is so useless cognitive wise ...and the people that make videos on crap like that seem to be low lives ...yeah I'm being kind of rude but I'm tired of people overhyping this medication and misleading people to think this is the limitless pill in the real world. my reason for the complaining is that I've taken provigil for 8 months and did not have any cognitive effects at all even racetams are better to this provigil ,modafinil.
mrvendetta123 (1 year ago)
I don't get why people complain about how he explains in the comment section. I listened to his video at 2.0x speed while working on something else, and it was very easy to understand and straight-forward. Very well explained.
Alicia Nieto (1 year ago)
Hi! I have a question, even if the video if somehow old, but I have a question I can´t find a straight answer for, and u said u had researched the topic... Do you have any idea about how can Dexadrine cause more physical side effects than Adderall for some people? It doesn´t seem to make sense. Both the little chemistry I know from college and the "research" I have been doing this past year support exactly what your video says, that it is the Levo the one that causes most of the side effects( heart punding, insomnia, etc...) but still I know Dex has worse effect on those areas than Adderall for a bunch of us...Do you have any idea of how or why that may be 0.0? I haven´t manage to get any straight answer besides "everyone reacts differently", but this sounds like a very weird kind of different, when one isomer has an effect it just shoudn´t have at all... So I´d appreciate your thoughts on it Thanks!
freemint (1 year ago)
You have to remember Dextroamphetamine is the compound that has the effect Dexadrine - has no additional side effects, has the quickest effect, has the most (100%) Dextroamphetamine (= most effect) per Mol/weight, the quicker release make misuse easier (snorting) Adderall - has additional side effects like heart racing, is nearly as quick as Dexadrine, has only 3/4 of the amount of Dextroamphetamine per Gramm, other compounds have nasty side effects, possibly interesting as party drug because of side effects, lower effect per Gramm than Dexadrine because of lower concentration of Dextroamphetamine Vyvanse - derivative of Dextroamphetamine which changes itself to Dextroamphetamine in the blood stream when an additional chemical group is removed, slower effect due to slower release, less misuse potential, no additional side effects (other than the side effects of Dextroamphetamine), lower Dextroamphetamine as Dexadrine, can not compare with Adderall Do no take Adderall it has nasty side effects, Dexadrine has the strongest effect, but with great power comes great responsibility, Dexadrine is more prone to misuse than Vyvans but it is cheaper. You decide.
Dee Lee (1 year ago)
Throw some Trypsyn onto the Vyvanse and cleve off the Lysine group and derive adderall !
Amanda Huerta (1 year ago)
You need labels when explaining. Great video!
Logan Muir (2 years ago)
You got a purtty moufh
Logan Muir (2 years ago)
Speak up son
Morgan Green (2 years ago)
Great video
A A (2 years ago)
Ah... this is why l-methamphetamine a legal otc medication for decongestion. Got it! Thanks!
Jim Neely (2 years ago)
but whatever... or something like that....
Jim Neely (2 years ago)
Thanks for clearing that up.............................???????????????????????????????????
Gabriel Palacios (2 years ago)
You suck at explaining
Gabriel Palacios (1 year ago)
Your mum is a bitch
Mcburnie (1 year ago)
sjw smurf
Mcburnie (1 year ago)
btw you look like a smurf lol
Gabriel Palacios (1 year ago)
John S (1 year ago)
maybe its because ur stupid
Warscrat Sasquatch (2 years ago)
Now this one knows the facts about adderall.
Stalkerx13 (2 years ago)
Why is it that Psychiatrists do not do brain scans for each person with ADHD so they can know what stimulant is perfect for the patient? All they do is a small questionair.
Valerie Allison (1 year ago)
Thagros http://www.amenclinics.com/
Valerie Allison (1 year ago)
Thagros Even though I'm in the US, My insurance doesn't cover the spec scans its almost $4000. but Dr Amen has an online test for the 7 types of ADD & it give you suggested supplements for each type.
Thagros (1 year ago)
That might be the case in the States. The data certainly suggest that. Not here in the UK.
Valerie Allison (1 year ago)
Thagros The Amen Clinics do spec scans but it's very expensive. My personal opinion why most psychiatrists don't do spec scans, they make more money not knowing exactly what is wrong with their patient's then the can guinea pigging them on a ton of scripts.
Valerie Allison (1 year ago)
Thagros The Amen Clinics do spec scans but it's very expensive. My personal opinion why most psychiatrists don't do spec scans, they make more money not knowing exactly what is wrong with their patient's then the can guinea pigging them on a ton of scripts.
ME2MR RCDCVC (2 years ago)
Did you make that art work in the back
Tarot the Hangman (2 years ago)
*thoughts on dexedrine** "i can put a right handed glove on my left hand. " " look i can flip inside out" " whos glove is this ?"
andrea brown (2 years ago)
Wow you just explained this so well thank you. I've been looking for this kind of information all over the Internet and you're the first source that I've found that isn't opinion based and biased. I never comment on videos but I'm currently on vyvanse so my brain feels like writing a paragraph over the information it just absorbed.
Mitchell Lister (2 years ago)
You look like that guy from kickass lol.
Liam Ryan (2 years ago)
wow that was so helpful man. PERFECT EXPLANATION. I'm in AUS and this drug just came in the market, will be getting 70mg Vyvanse for $32 as we have PBS (Pharmaceutical Benefits scheme) along with my normal 5mg Dex amphetamine IR for ADD. thanks again mate
Delicia Ricks (2 years ago)
thanks i have a way better understanding
Thunder Twonk (2 years ago)
Thank you very much for this explanation. I've been taking adderall IR for about 4 years now and was wondering what the difference was between the three. You have cleared this up. You earned my like.
TheFirstDeity (2 years ago)
Best, most concise explanation I've heard comparing these drugs.
Charles Jackson (2 years ago)
TLDR; Adderall takes immediate effect and requires multiple doses, Vyvanse takes approximately an hour to kick in and lasts longer; only requires one dose a day. Vyvanse (most likely) does not work properly or at least as effectively if snorted. Vyvanse is approximately $300 (as someone that has been prescribed a daily dose of Vyvanse, I can confirm this. In my experience, the price does not change based on the mg dosage.) The medications are very similar but, again in my experience and own research, have different side effects. From what I have asked two different doctors, Vyvanse is far more natural and safe than Adderall. Adderall is also far cheaper than Vyvanse (probably due to the whole patent thing) and, according to the person in this video can range from $10-$70, depending on where you're from. It is vital in my opinion to note that (at least in Canada) if you visit your psychiatrist, s/he can give you little prescription cards (no idea what they are actually called, sorry!) that you can give to the pharmascist whenever you are due for a prescription refill (they may not allow you to get a refill if it is more than something like 24-48 hours before necessary as they don't want to risk any possible prescription abuse on your part) and it is far cheaper that way. I believe it's something like $50-something for it in that way. (Only been on it a few months and my father is the one that keeps the cards on him and does refills so I don't know anything about it besides that, sorry!)
Darth Vegeta (2 years ago)
I love both pills. They make me very creative & deep. Our next president should deregulate both so more people can experience it's magic. My Communist Galactic Empire fanfic could be nicknamed a Vyvanse tale. http://swfanon.wikia.com/wiki/People's_Galactic_Empire
Wendell Goode (2 years ago)
With adult ADD I've tried Adderall, Dexedrine, Ritalin, Strattera, Pemoline and Modafinil. Modafinil wins hands down for me.
Yb (2 years ago)
this dude was just mad of being being ignorant about the drugs while on them and made a video lol
Casey Carnley (2 years ago)
This guy is smart as hell
crazy360playa (2 years ago)
this guy is definitely on adderall
CrispyKing (1 month ago)
Gabriel Stephen Roland white knight.
Gabriel Stephen Roland (1 month ago)
Lol im not even one of them. Just further proving my point you are salty about something and randomly lashing out.
CrispyKing (2 months ago)
Gabriel Stephen Roland Oh hi tweaker, goodbye.
Gabriel Stephen Roland (2 months ago)
CrispyKing bro lol you're salty about something and are deluding urself
CrispyKing (3 months ago)
Molly Hohenzollern Stewart You can barely form a sentence, not even a correct one. All you tweakers aren’t smart. Just cheating depressed losers at the end of the day.
Alucard Lledroc (2 years ago)
Good info....helped answer some questions.....thx =]
KoMa MeDiA (2 years ago)
This is an amazing video. thank you so very much. Honestly one of the best youtubers I have seen in a while that isn't comedy related.
Allegra Van Zuylen (2 years ago)
Do you know if Dexamfetamine Sulphate is another term for Dextroamphetamine? If same/different do you know what the equivalent dose of Dex-Add would be? Great video, you covered everything so clearly
Allegra Van Zuylen (2 years ago)
hey, whats your email?
Allegra Van Zuylen (2 years ago)
+Sons of Apollo sent you an email through your new page, thanks :)
Sons of Apollo (2 years ago)
+Allegra Van Zuylen Hello, I made a new channel. A major complaint of this channel was that this was simply too much information, nearly 500 videos on a wide spectrum of subjects. This new one focuses on pharmaceutical, health insurance, and related things. If you have a question I will be very glad to answer it, if I am able.
Alex Youknow (2 years ago)
didn't really expect a good video (no offense) but you did a great job explaining my friend
Sons of Apollo (2 years ago)
+Alex Youknow No offense taken, glad to be of assistance.
xpallodoc (2 years ago)
Do you take any of these drugs? Sounded like no. So do you take something. Please don't answer if you find this questions rude.
Pigsrock93 (2 years ago)
I took most of the different amphetamines, and people have different experiences with each other.
Aname (2 years ago)
Amazing and clear review, thank you! I have a question regarding statements made 03:00-03:25. Specifically you mentioned that the levoamphetamine in Adderall, releases or somehow effects the norepinephrine which I assume is a positive and necessary process, helping the dopamine get transported or attached to the receptors...? Would the absence of levoamph... in for example Vyvanse or Dexedrine have a negative impact on the norepinephrine release and therefor affect the dopamine negativley(in terms of absorbtion/transport/attachment)? Or does dexoamph... also take care for this norepineph... release and fully or to some degree? I am above all assuming norepinephrine release is positive...(maybe that is not the case?).
Sons of Apollo (2 years ago)
+Aname No it has nothing to do with dopamine release. It was added to extend the patent, since now it is technically a new compound. If anything it is detriment to concentration as it activates the sympathetic nervous system, which prepares the body for action, which in turn makes it more difficult for one to sit still. In England, where the company that makes Adderall is from, they never approved it, because for study purposes it is less effective than dextroamphetamine for the reason stated above, therefore they did not approve it because it would be a waste of billions of dollars. It was developed for the sole purpose to replace the money they were going to lose when the patent of Dexerdine (dextroamphetamine XR) expired.
Angelique Lopez (2 years ago)
Idk why but u remind me of Evan peters
Bee Stinger (1 year ago)
princess angeee lol maybe the hair style
Sacred Thyme (2 years ago)
i have lots of d-amphetamine and vvynese and hate them as they hurt my heart. then i got long acting types = extended release ... and they are so strong and hard on heart palpitations and attitude is bitchy ...
Find Flow (2 years ago)
k ten sec in. Here's your organic chemistry. Think of adderall as a filet from ruth chris. and a cheeseburger at 3am from mcdonalds is vyvanse ... End of organic conversation.. o boy he keeps sayin let hand right hand im outta here
Team_No_Sleep (2 years ago)
Keep it up!
Sons of Apollo (2 years ago)
+Stoney Khush (Madnastyman) Thanks man, will do!
Jim Lahey (3 years ago)
Twak is wack bro
Ricky Krajewski (3 years ago)
I don't think you can snort it. from what I know about digestion, protein breakdown takes place in the stomach and then continued in the small intestine by proteases. isn't this the case?
Tom Thomas (3 years ago)
hi I have really bad ADD not ADHD then agian my thoughts might be hyper, i was do you think modafinil or Vyvanse would be a better opetion, i have brain fog and im tired alot but the main thing is i lose shit all the time and I HATE to work and pay attention to tasks that dont interest me. Thank you sir love your vids
Jlyn limon (8 days ago)
GucciBalboa modanfinil is hard to get. It took me years. And the crazy thing is, modanfinil is a schedule below adderall and other stimulants. Meaning modanfinil is less likely to cause addiction 😰
Pepe (1 year ago)
Tom Thomas same boat as you, been on both back and forth for a very long time they kill you socially and really kill you as a person mentally vyvanse is alot better then adderall, adderall ruined me.
GucciBalboa (1 year ago)
Modafinil is hard to get, I tried buying some but it got seized by the border police and I got a warning
Dixie Normous (1 year ago)
Sons of Apollo, I'm sorry but I couldn't disagree more with your first statement. For you that is prob true, but there are many people in this world where no matter how hard they try or train to focus, they truly cannot do it. Believe me, I have tried everything to fix my ADHD without meds for many, many years and nothing works except medication. I truly believe some people's brains or the chemical balance in their body's is defective in some way and science hasn't been able to figure out the reason or cause of it so far. Maybe someday they will, but until then meds are the only answer for many of us.
Sons of Apollo (2 years ago)
+Tom Thomas Attention is a skill you have to train, like learning how to exercise. If you do decide to go the medication route, modafinil won't help you with ADD, with Vyvanse people tend to get good short term results, but the long term results can be quite variable, which can include worsening of symptoms long term. Its a risk, but if you feel it is justified it may be worth it to you. Vyvanse is a more expensive version of dextroapmphetamine. It is not superior to it, if you were going to take Vyvanse, I would look into that one first. Modafinil isn't approved for ADD, because it doesn't help with those symptoms, unless the cause of your inattention is due to some type of sleep disorder, then it may help. If you have further questions let me know, I was thinking of making another video in this area. Would love to hear more of the questions that people have.
Catherine (3 years ago)
Catherine (3 years ago)
I love a man who knows his orgo and can casually whip out a molecular set in conversation <3
ST L (1 month ago)
Catherine Marry me?
Catheryne Ramos (5 months ago)
Chode Master (8 months ago)
John S (1 year ago)
Meelsonwheels (3 years ago)
Real man. Dexedrine all the way
George Zonics (3 years ago)
Dexedrine spansules are my favorite but they hard as hell to find. I'm prescribed them and they work incredibly well.

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