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The Truth About L-Arginine

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The Truth About L-Arginine sets the record straight about the recent misinformation that is being promoted by other nitric oxide supplements who say that L-aginine is ineffective in producing nitric oxide in adults over the age of 40. The real truth about L-arginine is that this semi-essential amino acid is critically important in multiple metabolic pathways that can help you achieve optimal health. It is the proper combination of L-arginine with L-citrulline that gives you the greatest production of nitric oxide. This video on the truth about L-arginine helps you understand this as well as the other metabolic pathways that are important to your over all health and well being. This video also addresses the John Hopkins study that used a synthetic form of L-arginine called L-arginine HCL. The HCL or hydrochloride lowers potassium levels in the bloodstream, which can have a negative effect on heart function. Additionally the "Nitric Oxide Test Strips" promoted by Neo40 and CircO2 do not actually measure nitric oxide. What they measure is nitrite in your saliva. This video helps you better understand what these test strips actually measure and how they can not be accurately used to determine true levels of nitric oxide in your bloodstream. If you have any questions about the information in this video entitled The Truth About L-Arginine, then please contact me directly at 1-800-966-3012. The proper production of nitric oxide is critical to your cardiovascular health. It's time to help people cut through the misinformation and know exactly the truth about L-arginine, how it works best when combined with L-citrulline, to optimize the ability of the endothelium to create nitric oxide.
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Text Comments (369)
Kenny Huskisson (26 days ago)
I'm 54, I've had 6 heart attacks, open heart surgery, 2 strokes, type 2 diebeties, heart disease, what do you recommend please?
Daniel Hammer (23 days ago)
Hi Kenny and thank you for your question. Sorry to see that you have had some many cardiovascular health issues. My product of choice to harness the benefits of nitric oxide therapy is ProArgi-9+ as it is the only clinically proven L-arginine supplement in the market. And it has been recognized for the last 5 years by being listed in the Physicians' Desk Reference. If you send me an email to dan@agingnomore.com I can send back to you some pricing options. Please let me know if you have a US zip code. And if not, then what country you live in so that I can give you some pricing information. Have a Blessed Day! Dan
Matteo Orlandi (1 month ago)
how to determine the right combination of l - arginine and l - citrulline ?
Daniel Hammer (1 month ago)
Hi Matteo, and thank you for your question. If you're just taking L-arginine and L-citrulline than according to Dr. Louis Ignarro (who won a Nobel Prize in Medicine for his research in this area) he would say you need 4-6 grams of L-arginine and 250 to 1000 mg of L-citrulline. As well as some additional ingredients to optimize nitric oxide product. My product of choice is ProArgi-9+ from Synergy Worldwide. It is the only clinically proven L-arginine supplement in the market place. It include both L-arginine and L-citrulline but also contains other need ingredients to optimize the ability of the endothelium to produce nitric oxide. Here is one of my videos on this product https://youtu.be/N0M2c17etDc Have a Blessed Day! Dan
bobluhrs (1 month ago)
Sodium nitrite was used in drinking water for rats who were subjected to a high atherogenic diet. All the rats who got the sodium nitrite did not develop atherosclerosis, while the ones who did not, all got it and died. Nitrite levels in the body, which test strips can measure in saliva, do predict nitric oxide in the blood. I use nitrite-driven supplements and believe me, it works great by itself in reducing blood pressure and increasing energy, even where arginine-driven ones don't. I'm 72, so arginine working or not working is a concern. However, I still take both the arginine-citrulline formula and the sodium nitrite supplements.
Daniel Hammer (1 month ago)
Thanks for sharing your experience on how nitric oxide therapy has benefited you health. Have a Blessed Day! Dan
Visitor (2 months ago)
I trust Suzy Cohen and her studies.
Daniel Hammer (2 months ago)
Hi Visitor and thank you for your opinion and belief in Suzy Cohen. Unfortunately, if all of America trusted "her studies", then over 75% of Americans would not be able to harness the benefits of Nitric Oxide Therapy for improved vascular health. I'll trust the 3 American researchers who were awarded the 1998 Nobel Prize in Medicine for their discover on how the lining of your vascular system called the endothelium converts L-arginine to nitric oxide, the master signaling molecule of your entire cardiovascular system. Have a Blessed Day! Dan
Kool Kroozer (2 months ago)
False information ! I am over 50 and feel like a teenager after taking 2 of these tablets daily !
Daniel Hammer (2 months ago)
Thank you for sharing your testimonial on how L-arginine benefits human performance for those over the age of 40. Have a Blessed Day! Dan
daehttub (3 months ago)
5g Arginine the spot for lifting?
Daniel Hammer (3 months ago)
Sorry but I don't understand your question. Dan Hammer
ex catholic (5 months ago)
Wow, awesome video . Big thanks! I tried everything to lose the extra pounds I gained between age 49 to 51 and nothing worked despite being a high level athlete! But within 10 days of using L arginine, I lost the weight, effortlessly, without any calorie cutting and on a high fat diet!
Daniel Hammer (5 months ago)
Hi ex catholic and thank you for sharing how L-arginine helped you make some very positive changes to your health. Have a Blessed Day! Dan
Mourad121 (6 months ago)
ARGININE IS GOOD FOR EVERYBODY..............SIR. STOP HELPING BIG PHARMA.....................SIR.
Daniel Hammer (6 months ago)
Hi Paix. Thank you for your comments even though they are misguided. There is nothing in this video that has anything to do with Big Pharma. The whole point of the video is to counter the misinformation that L-arginine is bad for people over the age of 40. And since L-arginine is a nutritional supplement Big Pharma has nothing to do with the sale of this nutritional supplement. Have a Blessed Day! Dan
p.messinger (7 months ago)
Thanks for this very informative presentation!
Daniel Hammer (7 months ago)
You're welcome!
gerthie (7 months ago)
Brilliant info dan
Frank Collins Jr (8 months ago)
HOW MUCH OF EACH ONE SHOULD A 225LB MAN TAKE DAILY?
mark hughes (8 months ago)
Brilliant! Thank you.
Daniel Hammer (8 months ago)
Your Welcome!
Shadhy Muhammed (9 months ago)
I'm going gym...i am having fat about 5 kg...now I'm workouts for muscle building.... But I feels tiredness while workouts...(bcz I'm in a diet )can I use lrg9 for getting energy???.will it gain my fat
Imwatchingyou48 (10 months ago)
Awesome video Dan. Thanks
Daniel Hammer (10 months ago)
Your welcome and please share it with others. Have a Blessed Day! Dan
John Mtembezi Inniss (1 year ago)
A superb, peerless presentation. Excellent. One minor detail: the university that you cite is the Johns Hopkins University (with an -s). I know because I taught there for three years in the late 1990s.
Daniel Hammer (1 year ago)
Hi John, thank you for your comments. I'm glad that you liked the video and thank you for the correction on Johns Hopkins University. I didn't catch it in the editing process and once the video is up it can't be edited. Have a Blessed Day! Dan
John Smith (1 year ago)
Arginine does not work. Take sodium nitrite to raise NO. It will cost a few bucks for a years supply.
Daniel Hammer (1 year ago)
Hi John and thank you for sharing your approach to using sodium nitrite. Please continue to keep me posted. First to answer your question. I take 5 grams of free form pharmaceutical grade L-arginine per day made through a biofermentation process using non-GMO corn or maize. However, it is more than just using l-arginine for the creation of nitric oxide. To use a single ingredient will only give you a temporary effect. This applies to l-arginine as well as your use of sodium nitrite to create nitric oxide. Once each of these ingredients are used then the ability of your body to take the metabolites and reform the needed precursor for more nitric oxide production is very limited. Other key ingredients are needed if you want to get long term production of nitric oxide. So I combine the l-arginie with other ingredients like l-citrulline, vitamin D3 and vitamin K2, pomegranate fruit concentrate as well as some other ingredients so that I can get higher production of nitric oxide over a longer period of time. This then provides greater benefits in harnessing the power of nitric oxide therapy to support blood flow and improved cardiovascular health. One final comment and that the need for l-arginine goes beyond just the creation of nitric oxide. As I tried to point out in my video l-arginine fuels 7 different metabolic pathways that are important for optimal health. So when people state that l-arginine doesn't work or that it is "bad for you if you're over the age of 40" I take exception to those comments because they are not true. Have a Blessed Day! Dan
John Smith (1 year ago)
If arginine actually converted to NO to any significant extent then body builders taking 10g a day would be passing out from low blood pressure. Taking even 100mg a day of nitrite at first might be too much for some people! That's how good it is at raising nitric oxide! I started on 40mg a day yesterday, and will slowly increase to see how high for the most beneficial effect. I'm sure you take it everyday... how much do you take each day?
Daniel Hammer (1 year ago)
Hi John and thank you for your defense of your position for using the nitrite/nitrate pathway. I'll leave it for others to decide which pathway is better for the production of nitric oxide. However, if you are going to go down the nitrite/nitrate pathway, regardless of the initial sourcing, then you better make sure you're consuming arginine to help fuel the urea cycle to clear your system of urea and ammonia waste products that come from nitrogen metabolism. Have a Blessed Day! Dan
John Smith (1 year ago)
The pathway to make NO from arginine is complex, and under tight control so only a certain amount is made each day even if large amounts extra are ingested. Nitrite on the other hand only has to have a single electron reduction back to NO making it the best way to boost NO levels. What I just said is well known to doctors/scientists or anyone skilled in the art. Nitrite is not dangerous- perhaps because it is sooo cheap, and such an effective treatment for a huge range of diseases such as heart disease, cancer, autism, depression, impotence, etc there is an effort to make malicious deliberate lies about it, and say it is dangerous- when it is not. Pure nitrite powder is better than beet which only has a small percentage nitrite/nitrate in it. You know everything I jut said but I will leave it here in case someone else doesn't, and reads it.
Daniel Hammer (1 year ago)
Hi John, thank you for your opinion about L-arginine. I've decided to leave your comment up for two reasons. First, I do not agree with your statement "Arginine does not work." This amino acid is essential for good health. Second, I would caution people from using sodium nitrite for the creation of nitric oxide for the following reasons: a. sodium nitrite while cheep has the same limitations in the production of nitric oxide as beet root. However, beet root is safer. b. sodium nitrite has toxicology warnings https://www.ncbi.nlm.nih.gov/pubmed/12563346 (one of many studies you can find). c. we get plenty of sodium in our diet so if you want to use the nitrite/nitrate pathway for the creation of nitric oxide, then use beet root powder, which would still be inexpensive but saver then using sodium nitrite. Have a Blessed Day! Dan
Stephen Youngblood (1 year ago)
Watermelon Rinds are best source of L-Citrulline
Daniel Hammer (1 year ago)
That's true.
Jerseyhighlander (1 year ago)
Excellent information, very well presented. Thank you.
Daniel Hammer (1 year ago)
Your welcome and have a Blessed Day! Dan
Neophyte (1 year ago)
I appreciate all this great info, but I'm not convinced I need everything contained in ProArgi9+ if my diet is otherwise balanced and complete. Only L-citrullline seems to be really worth supplementing. As a heavily plant-based eater I get enough of the vitamins and anti-oxidants from fruit and plenty of L-Aginine from pumpkin seeds, soy and other beans.
garyperez (1 year ago)
Thank you so very much for this informative 20-minute lesson. I've been supplementing with L-Arginine, L-Glutathione, D3, Super K, Moringa, Maca, Potassium, Zinc, NAC, B-complex and have yet to include L-Citrulline... I am 55 and in pretty good condition. My question: how much L-Citrulline should I add to the above? My L-Arginine intake is about 5-8 grams per day at the moment. Thank you very much!! ;)
garyperez (1 year ago)
Thank so much, for your speedy response! Very grateful. Big warm smiles, at ya'!!
Daniel Hammer (1 year ago)
Hi Gary and thank you for the comment and question. Given what you're doing I would suggest somewhere between 500 - 1000 mg of L-citrulline. Have a Blessed Day! Dan
Brian Cousins (1 year ago)
Thank you for the presentation but Is there some reason that no recommendations are provided as to the quality and quantity of L-Argenine and L-Citrulline to be taken?
Daniel Hammer (1 year ago)
Hi Brian and thank you for your comment and question. Yes there is a reason. I wanted this video to not be biased towards any product and just counter the misinformation put out by nitrate/nitrite manufacturers who tell the general public that L-arginine is not beneficial if you are over the age of 40. This is not true. In answer to your question pharmaceutical grade is always best as food grade used in most supplements varies widely in purity and potency. The ratio of L-arginine to L-citrulline also depends on the other active ingredients in the product to help enhance nitric oxide production. As a general guideline 5 grams for L-arginine and 200 to 1000 mg for L-citrulline. The product of choice for me and the one I use for my clients is ProArgi-9+ from Synergy Worldwide as it has been listed in the Physicians' Desk Reference for the last 4 years and it is the only Clinically Proven L-arginine supplement in the market. If you want more information on this product, then watch this video https://youtu.be/wdyf_dJZer4 or email me at dan@agingnomore.com Have a Blessed Day! Dan
Alan Mauser (1 year ago)
Daniel sorry tu tell you you are completly wrong...ask dr. Louis ignarro the discoverer of l-argine who got the nobel prize for this descovery...he uses l-arginine every day he is 70 years old and runs complete marathons
Our Synergy Family (1 year ago)
Hi Alan and thank you for your comment. Unfortunately you must not have watched all of the video or I did a very poor job of communicating. But the whole purpose of this video was to defend the use of L-arginine. Companies like Neo40, who use the nitrate/nitrite pathway for the production of nitric oxide, like to tell people that L-arginine is bad for people over the age of 40. This video was produced to let people know that that is completely untrue. That L-arginine is essential to everyone no matter your age. So I'm in complete agreement with Dr. Iganrro. Have a Blessed Day! Dan
Kathy Ridge (1 year ago)
So, I'm concerned about two things: 1. If broccoli, spinach, beets, etc are creating the inferior (and it seems harmful) pathways to NO via nitrates/nitrites, I'm wondering why such otherwise nutritional foods such as they are, have this negative effect in the body. 2. In another video you are demonstrating how L-arginine, L-citruline and NO are best taken by supplemental form instead of eating the amounts of watermelon, beans, etc to achieve the same amounts in the body. I'm wondering why, when nature normally provides sufficient amounts of micro and macro nutrients through vegetables and fruits, would this be the case That nature doesn't provide enough of these very important nutrients in these foods. It just doesn't make sense to me, sorry. Any enlightenment would be appreciated.
Daniel Hammer (1 year ago)
Hi KCR and thank you for your response. If you go and look up Genesis 2:29-30 you will see "Then God said, 'Look! I have given you every seed-bearing plant throughout the earth and all the fruit trees for your food. And I have given every green plant as food for all the wild animals, the birds in the sky, and the small animals that scurry along the ground - everything that has life." And that is what happened." If I interpret this correctly everything in the beginning was founded on plant based nutrition. That changed when Adam and Eve were kicked out of the Garden of Eden. And the nutritional quality of food has also decreased over time. If you read about Caleb you will see that plant based nutrition was key to his health. And if you read about Daniel and his 3 friends you will see that plant based nutrition was superior to animal based nutrition. Unfortunately with modern farming and the depletion of soil minerals our food today does not have the nutritional value that it did even 100 years ago. Processed food has processed out many of the key nutrients and vitamins that are essential for good health. It's not God's fault but our fault and all good supplementation does is help us get back to much that we are missing from our food. Even our ability to produce nitric oxide. Have a Blessed Day! Dan
Kathy Ridge (1 year ago)
Thanks so much for your response, Daniel. I'm troubled though, because if nitric oxide is so important in our systems, and it is, I'm concerned that one would have to eat such an enormous amount of the foods which provide it. I'm of the opinion that our creator provided foods in the logical quantities and types to further our health through plant based diets. I'm thinking that killing animals is not really a part of that provision, but of course, I wasn't around to get cc'd on the creation file. Plus, I doubt that supplements were a part of it. With such an important nutrient, I find it really hard to believe that the vegetable component other than beets is so far out of our reach because of the quantity needed and it's obviously seriously needed in our diets. Something seems to be missing in this scenario. It's just not logical.
Daniel Hammer (1 year ago)
Hi KCR and thank you for your two items. You will not get much nitric oxide production out of broccoli and spinach. However, you will get a temporary increase in nitric oxide production via beets. As long as your urea pathway is working you don't have any concerns in this area. It's when others tell you that the L-arginine pathway is bad for you if you over the age of 40 that you need to be concerned. The amino acid L-arginine is critically important for every age group especially as we age because your body uses it to fuel 7 different metabolic pathways. Urea being one of them. Regarding your second point, I'm not against getting the L-arginine and L-citrulline from your food. However, if you're trying to get a large enough amount into your system to have a therapeudic benefit, then you will need to address your caloric intake. Because foods like beans and chicken all have calories and the amount of vegetables you would need to consume would be larger than most people would eat. So a combination of supplementation with good food choices is always the best route. At least in my mind and practice. I hope this helps. Have a Blessed Day! Dan
Ramon Gonzalez (1 year ago)
Hello !!! Daniel Hammer its seems to be working for people over 40 ..I think you are part of PHARMA !!!
Christopher Allan (3 months ago)
It depends on your endothelium function. The less endothelial cells, the less effective L-arginine will be.
Daniel Hammer (1 year ago)
Hi Dohn, Thank you for the kind comments and I received your email. I just sent you back a response on which product that I would recommend. It is ProArgi-9+ from Synergy Worldwide. I sent you a link to order this product. Please let me know via email if you have any additional questions. Have a Blessed Day! Dan
Dohn Solis (1 year ago)
I apologize for the ignorant comments of people who can't even take the time to watch the video but nonetheless is more than ready to dole out their unsubstantiated and idiotic opinions. Awesome job on the video Dan! Is there any brand of L-Citrulline you recommend? Thanks in advance.
Daniel Hammer (1 year ago)
Hi Ramon and thank you for watching this video. I'm a bit confused by your comment though. One of the purposes of this video is to help people understand that nitric oxide therapy through the use of L-arginine works for all people even those over the age of 40. And your comment that I'm part of PHARMA wouldn't apply to me since what I promote is a natural method through the use of the amino acids L-arginine and L-citrulline as well as other natural ingredients to properly boost nitric oxide production. Have a Blessed Day! Dan
Frank Zen (1 year ago)
Works for me! I measure before and after and it consistently lowers my BP...
Daniel Hammer (1 year ago)
Thank you for sharing your results. Have a Blessed Day! Dan
Dianne Anderson (1 year ago)
A another YT seller's ad!!!!!!!
James Stapleton (1 year ago)
When added with the proper components it works over 40. Forever living has blended all these together for best results. As it has done for me at 60.
James Stapleton (1 year ago)
🍹
Kyle A (1 year ago)
what is Dr ignarros view on the jhohs Hopkins study? his book was written before the study right? I've read a study that said that arginine creates inos which of course is inflammation inducing, this is one of the reasons I don't take it. your thoughts? does citruline do this, or only enos? does pomegranate reduce dht in healthy cells or only prostate cancer? thanks for the video!
Daniel Hammer (1 year ago)
Hi Kyle! Thank you for the questions. First, I don't know what Dr. Ignarro thinks of the John Hopkins study. My view is in the video The Truth About L-arginine. It was most likely not the L-arginine but the HCl carrier molecule that they used that caused the problem. You can watch the video for more details. Arginine doesn't create inos. This is an enzyme used by the immune system to create nitric oxide from L-arginine. Nitric oxide is created in the vascular system by the enos enzymes of the endothelium. Typically this does not cause inflammation but actually prevents inflammation. In the body L-citrulline is converted to L-arginine and then would be converted to nitric oxide through the enos pathway. Hope this helps. Have a Blessed Day! Dan
Vic Toza (1 year ago)
It's pronounced "ar-ji-neen," not "ar-ji-nine."
mathetes (1 year ago)
A simple test, pick up some Berkeley N.O. test strips (accurate & cheap ) & get your baseline & then test again a few hours after this supplement. if your N.O. levels do not rise, there's your answer. Hint, the best way to elevate N.O levels is a good diet & beet juice & surprisingly a dry sauna for 15 min. Also stay far away form anti septic mouthwashes, your body's natural saliva is crucial for N.O.production.
Daniel Hammer (1 year ago)
Hi Jimmy and thank you for your comments. Unfortunately, you are spreading false information. The Berkeley NO test strips do not and I REPEAT do not measure nitric oxide levels. This is covered in this video. What they measure is nitrite levels in your saliva. Period. They then associate that with improved nitric oxide levels. And companies that use beet juice to produce NO through the nitrate/nitrite pathway mislead people in this area especially when they want to compare it to the L-arginine pathway for the creation of nitric oxide. Nitrate consumption will product nitrite to activate the test strips. NO produce by the endothelium through L-arginine or L-citrulline will not show up on these test strips because this pathway does not produce nitrites in the body. And while your last statement is truthful and correct your information on the Berkeley NO test strips is not. Have a Blessed Day! Dan
Degnte Abdeta (1 year ago)
My project is based on the importance of the NO which associated with a metabolic disorder causing endothelial dysfunction. The eNOS enzyme increased the synthesis of NO using the L-arginine. Post-translational methylation of arginine residues in proteins leads to generation of NG-monomethylarginine (MMA) and both symmetric and asymmetric dimethylarginine (SDMA and ADMA) and I have to find out if an increased ADMA found in CVD patient is a responsible to altered the gene (given gene ) which is have factor of cellular proliferation in cell cycle of eukaryotic cell. To answer this questions which pathway of nitric oxide synthesis is a good example? as it has many pathway. Do you think L-arginine -citrulline =nitric oxide other than other pathway? Thank you
Daniel Hammer (1 year ago)
Hi and thank you for the information you shared. Personally I'm a firm believer that the best pathway for the creation of NO is the endothelial pathway. And the best way to optimize this is a combination of the following key ingredients: l-arginine, l-citrulline, vitamin D3, vitamin K2, red wine extract, and pomegranate fruit concentrate. While there can be some other ingredients added to this mix, it is these 6 key nutrients that help to optimize the eNOS ability to produce NO at higher levels over a much longer period of time. Have a Blessed Day! Dan
Frank Logrim (1 year ago)
so im fine just taking L arganine as both does the same job?
Daniel Hammer (1 year ago)
Hi Frank and thank you for the question. If you are only going to use L-arginine then you will need to take 5 grams 3 times per day. A better program would be to combine 3-5 grams of L-arginine with 1 gram of L-citrulline and do this twice per day. And an even better program would be to effectively combine L-arginine, L-citrulline, pomegranate fruit concentrate, vitamin d3 and vitamin k2 to enhance the ability of the endothelium to optimize nitric oxide production. If you have further questions, then please email me at dan@agingnomore.com Have a Blessed Day! Dan
Sam D (1 year ago)
This site needs to be maintained.  Viewers are not getting replies.  Pointless to put info up then leave people stranded.
Christopher Allan (3 months ago)
What nitric oxide production enhancer do you use?
Sam D (1 year ago)
Ok, thanks for that.  I know I can't get my notifications either.  I swear sometimes it's deliberate especially with certain topics if you know what I mean.
Daniel Hammer (1 year ago)
Hi Sam. Thank you for your concern. I apologize as I sometimes don't get the notification from YouTube that a comment has been posted and with all the videos I have it is hard to see all the comments without this notification. Have a Blessed Day! Dan
Serge draeko (1 year ago)
Hi Daniel, first i would like to thanks you for this video that i've found very useful to understand the matter, but i would like to ask you one thing. I'm taking since a few days a pure gel extract of Korean Ginseng roots that in my opinion is showing already some benefits in my overall health, my question is, can i combine L Arginine and/or L Citrulline with it and if so in which doses i should take them? thanks
Daniel Hammer (1 year ago)
Hi Serge and thank you for your question. Sorry for the delay in answering but I didn't see it until now. Yes you can combine all of it together and I would recommend 3-5 grams of L-arginine with 1 gram of L-citrulline. And you might want to do that twice per day depending on how aggressive you want to be with nitric oxide therapy. Have a Blessed Day! Dan
Josh Bitterman (1 year ago)
Hello, one question is it alright for a teen to take l arginine?
Josh Bitterman (1 year ago)
Awesome! Even early age teens like 14?
Daniel Hammer (1 year ago)
Thank you for the question.  Yes, but I would suggest no more than 5 grams on a daily basis.  Unlike an older adult who might need more because their nitric oxide production has decrease, this would not be the case more most teenagers.  Have a Blessed Day! Dan
Mitch Hill (1 year ago)
Hi Daniel is L-Arginine HCI bad to use. I have exercise from since a teenage at least 4 time a week and now I am in my 40s that haven't change. product by ( Doctor's Best)
Mitch Hill (1 year ago)
Thank you vey much for the info but I found it very hard to find it in the UK with out HCI
Daniel Hammer (1 year ago)
Hi Mitch and thank you for the question.  I personally would not use L-arginine HCl as the hydrochloride reduces potassium levels in your blood system.  While this might not have affected you it can effect others.  Plus there are plenty of other better L-arginine supplements that do not use HCl as a carrier molecule.  Have a Blessed Day! Dan
Landon Eaves (1 year ago)
I thought arginine had little to no absorption rate compared to citrulline and citrulline is converted to arginine in the body? what would be the point of taking them together if your getting almost the same amount of arginine with just citrulline alone?
Landon Eaves (1 year ago)
Gene Mar to sum up what I recommend is 6000-8000 mg citrulline malate 1000 IU vitamin D3 + 100mcg vitamin k2 (as mk-7) super B complex and fish oil. those are the only supplements I take as far as health-wise goes.
Landon Eaves (1 year ago)
Gene Mar L arginine has very low bio availability. citrulline and even more so citrulline malate is far more bioavailable and increases blood arginine levels even more so than supplementing with arginine itself. so I say save your money, don't buy arginine and invest in more citrulline or even better citrulline malate. be careful with fat soluble vitamins like A, D, and E as they have higher toxicity rates than water soluble vitamins like B and C. D3 is perfectly safe if supplemented with vitamin K2 (as mk-7) as far as vitamin C and folic acid just take a B complex. most include vitamin C and have very safe dosages. do your research on vitamin E. ala is the least bioavailable of all omega 3 fatty acids but you're likely to find a lower dose in an omega 3 fish oil complex with dha and epa. higher doses should be safe do to the deficiency rate of omega 3s.
Gene Mar (1 year ago)
Landon, I just read Dr. Ignarro's book and he proposes, once a day, 4-6 grams L-arginine, 200-1,000 mg L-citrulline, 500 mg Vitamin C, 200 IU Vitamin E, 400-800 mcg Folic Acid, and 10 mcg Alpha Lipoic Acid. Only question I have is with the last supplement since the vitamin stores only carry 100 mcg Alpha Lipoic Acid, which I bought and am now using. I am only using pure base L-arginine and L-citrulline, no malate, etc. Please let me know your comments regarding this information. Thanks!  Daniel, please feel free to weigh in on this for everyone's benefit. Thanks!
Landon Eaves (1 year ago)
Gene Mar 10g of citrulline and arginine a day is way to much. maybe 6g citrulline in the form of citrulline malate and 4 grams arginine because of its low bioavailability and digestion problems it causes.
Gene Mar (1 year ago)
Daniel, thank you for that very informative video. Do you have any suggestions for the proportions and total amounts of L-arginine + L-citrulline which should be taken every day? For example, 5 grams of each mixed together for a 10 gram total, taken twice a day? I suppose the proportion of each is important, and may not be optimally set as 1 to 1. Thanks for your help!
Kurtis Tatsch (2 years ago)
Are there any specific supplements you would recommend for people over 40 to produce Nitric Oxide?
Daniel Hammer (2 years ago)
Hi Kurtis and thank you for the question.  The product that I use with all my clients is ProArgi-9+ from Synergy Worldwide.  I've been using this product for 8 years and have had great results especially for those over the age of 40.  It is the only "clinically proven" l-arginine supplement in the market.  And it is the only recognized l-arginine supplement by the medical community.  It's been listed in the Physicians' Desk Reference for the last 3 years.  Plus there are 262 verified quality assurance steps that go into the manufacturing of this product to guarantee all label claims.  If you want more information on this product then please click on the following link  https://www.youtube.com/watch?v=wdyf_dJZer4  Or you can call me at 1-800-966-3012.  Have a Blessed Day!  Dan
MrFerinjo (2 years ago)
Hi Dan, ca you please advise which form of Arginine should I take, Free form or with HCL to stimulate NO and muscle growth? Is HCL form dangerous for a healthy individuals? I am a healthy 37 yr old man. Thank you
Daniel Hammer (1 year ago)
Hi and thank you for your question. Free form L-arginine is always the best choice especially if it is pharmaceutical grade. I'm not a fan of HCl in any form for two reasons. One, when attached to L-arginine you lose about half the amount taken in because HCl makes up 45-55% of the intake. Second, even in healthy people it can reduce your potassium levels, which then can results in muscle cramping if you're working out. My product of choice for my clients is ProArgi-9+, which uses 5 grams of pharmaceutical grade l-arginine per serving with the other needed ingredients to optimize NO production. Plus it's the only clinically proven L-arginine supplement on the market. If you have additional questions about this product, then email me directly at dan@agingnomore.com. Have a Blessed Day! Dan
Emma Connolly (1 year ago)
MrFerinjo i may be able to help if you are still looking for l'arginine supplementation 😊
abhijit podder (2 years ago)
Sir if taken for body building purpose(increasing blood flow to the muscles) does L-Arginine supplement need to be cycled or it can be taken year long? also if someone's blood pressure is little lower is it safe to consume? plz reply and thnx in advnce.
Daniel Hammer (2 years ago)
Hi and thank you for the questions.  You do not need to cycle on and off with L-arginine.  It is a semi-essential amino acid so your body needs it as it fuels multiple metabolic pathways.  Regarding the low blood pressure.  The healthier your endothelium the better able it is to properly regulate your blood pressure.  From my experience I've not found this to be an issue unless someone was taking certain types of high blood pressure medications.  In this case their blood pressure may continue to go down so they need to work with their physician to wean themselves off of the medication since nitric oxide is doing what it is meant to do, which is help maintain a normal blood pressure through proper vasodilation.  Have a Blessed Day! Dan
Jaimie Renee (2 years ago)
you didn't give the proper combination so no this video did not help
Jaimie Renee (2 years ago)
Thank you, I watched the whole thing waiting for what dosages were best, but just basic dosage.. thank you very very much!
Daniel Hammer (2 years ago)
Hi Jaimie and thank you for your comment.  The proper combination can vary based on the other ingredients you're combining.  The purpose of the video was to help people understand that the use of L-arginine is a valid pathway for anyone even if your over the age of 40.  The book NO More Heart Disease by Dr. Louis Ignarro is still the best book on understanding nitric oxide therapy through the use of L-arginine.  If you're just focused on two ingredients the amount of L-arginine is somewhere between 4 to 6 gram and the amount of L-citrulline is somewhere between 250 to 1000 mg.  A lot depends on the purity and potency of the amino acids and what other ingredients you combine them with.  Hope this additional information is helpful to you.  Have a Blessed Day! Dan
Krish Singh (2 years ago)
hey sir i am indian i train my muscles at gym i am 20 year old i take 5 mg as pre workout before workout and i eat lots protein shakes to but it doesnt work i take tablet plz tell me which time should i take and i also drink water during when pulls some weight that i have problem some times energy low some time suddenley it happened plz suggest me some idea
Frank mc cann (4 months ago)
thanx so much. lost 40 lbs and got in shape due to u and jerry brainum.
Daniel Hammer (2 years ago)
Thank you for sharing and yes you are correct in that nitric oxide therapy is just one part of the overall equation.  Another key area would be his microbiome and how it is effected by the food choices he is making.  Have a Blessed Day! Dan
I don't know (2 years ago)
Nitric oxide is only one piece of the puzzle my friend. A large piece but not all the pieces. Get a blood test and check all your hormones and blood and all the tests you can get. This will tell you a lot about yourself. Oh and you could be overdoing some protein.
Jon T (2 years ago)
Thanks so much for this info. Can i subsitute Cirtuline Malate for the L-Citruline component ?
Charity Strong (2 years ago)
#Hotmail Another factor in heart disease is the consumption of ruined essential fatty acids, EFA's. EFA's line the endothelium. Omega 6 and omega 3 are EFA's. Omega 6 lines the endothelium. Most of the omega 6 consumed today is ruined by processing and heating. Virtually all vegetable cooking oils are processed oils such as corn, soy and canola. Most breads and baked goods are made with it too. Virtually anything found on a grocery shelf that contains these oils are ruined. Cholesterol transports omega 6 via a lipoprotein. The cholesterol combines with the omega 6 and is called cholesterol esters. It is important to replace damaged omega 6 with unprocessed unheated omega 6. A good source is sunflower oil. It is high in omega 6 (65%). A teaspoon or 2 a day is all that is needed, but it must be virgin cold pressed unrefined and unheated. It can be obtained in health food stores or on the internet. Amino acids alone is not the answer. @Our Synergy Family
Craig Harrison (1 year ago)
I also found that virgin cold pressed unrefined and unheated coconut oil is packed with EFA's. Good brain food!
Charity Strong (2 years ago)
#dream ah I know it is spelled Arginine but it is pronounced AR-JE-NEEN @Daniel Hammer
Charity Strong (2 years ago)
#juan cruz #Hotmail Another factor in heart disease is the consumption of ruined essential fatty acids, EFA's. EFA's line the endothelium. Omega 6 and omega 3 are EFA's. Omega 6 lines the endothelium. Most of the omega 6 consumed today is ruined by processing and heating. Virtually all vegetable cooking oils are processed oils such as corn, soy and canola. Most breads and baked goods are made with it too. Virtually anything found on a grocery shelf that contains these oils are ruined. Cholesterol transports omega 6 via a lipoprotein. The cholesterol combines with the omega 6 and is called cholesterol esters. It is important to replace damaged omega 6 with unprocessed unheated omega 6. A good source is sunflower oil. It is high in omega 6 (65%). A teaspoon or 2 a day is all that is needed, but it must be virgin cold pressed unrefined and unheated. It can be obtained in health food stores or on the internet. Amino acids alone is not the answer. @Our Synergy Family @Adrian Cecato
frank ertolacci (2 years ago)
if you breathe nitric oxide from a cylinder in very small amounts would this work to reduce or rid the body of of blockages in the arteries
Hotmail (2 years ago)
So after 20 minutes of watching this why do you not tell us what is the proper dosage that we should take(How much L-arginine and how much L-citrulline should we take in a dose) , when we should take it (empty stomach, full stomach, etc),w and how often (once a day, twice a day, etc.). Also, I take L-arginine HCL, it wasn't clear as to whether this is acceptable. You didn't even answer what brands or type of L-arginine or L-citrulline we should take or what to stay away from. COMPLETELY FUCKING USELSS! YOU GAVE US THE SCIENCE NONE OF WHAT WE NEED! IF ANYONE CAN ANSWER MY QUESTIONS PLEASE DO....OTHERWISE THIS WAS A WASTE OF FUCKING TIME....ABSOLUTELY NO CLEAR ANSWERS AS TO WHAT TO DO!!!!!
Gene Mar (1 year ago)
Hotmail, absolutely! There are commercial interests involved which preclude anyone revealing the "secret formulation". LOL!
Daniel Hammer (2 years ago)
Thank you for sharing your experience with ProArgi-9+.  While I don't talk about this product in the video it is the one I use with all my clients.  Have a Blessed Day! Dan
A MILLION GEARS (2 years ago)
This stuff really works!!! I also use the Proargi9+... I hear It's best taken 30 mins before or 30 mins after you eat. Twice daily. I take it upon waking up following a 15-30 min high intensity interval training workout and then I take it before bed. Big Pharma hates this stuff!!!!
Hotmail (2 years ago)
Thank you for the prompt reply.
Daniel Hammer (2 years ago)
Hi Hotmail - First off clean up your language and if you send me back abusive language I'll delete your comment.  Now to answer a couple of your comments.  First off the amount of L-arginine and L-citrulline is dependent upon the quality of the product you're using.  If you read the book NO More Heart Disease by Dr. Louis Ignarro will recommend 4-6 grams of L-arginine and somewhere between 200 to 1000 mg of L-citrulline with other key ingredients.  Again, the purity of the L-arginine and L-citrulline is key.  Most companies use food grade amino acids so the purity and potency is all over the board.  Second comment - it is best to take these amino acids on an empty stomach usually before a meal by about 30 minutes or more.  However, some people do better if they take them with food.  Just make sure that if you take them with food there is no sugars in your meal.  Sugar will bind to the amino acids and change their absorption properties.  How often per day depends on the quality of what your taking.  A well formulated product will allow you to take if twice per day to get maximum benefit.  The video is pretty clear on the use of L-arginineHCl.  Do use it!  If you're taking large amounts the HCl is lowering your potassium levels which can lead to muscle spams.  I tried not to recommend any brands in this video because I didn't want to promote any company.  Personally I use ProArgi-9+ from Synergy Worldwide.  And I use this product with all my clients.  It's the only L-arginine supplement listed in the Physicians' Desk Reference (3 straight years) and it is the only "clinically proven" l-arginine supplement in the market.  It's clinically proven to produce higher amount of nitric oxide than L-arginine alone.  And it's clinically proven to prevent vascular inflammation in two specific ways.  Here's a link to one of my videos on this product ProArgi-9+ Advantage From Synergy Worldwide https://www.youtube.com/watch?v=wdyf_dJZer4 Have a Blessed Day!  Dan
daphoenixto (2 years ago)
Dan hello I live in Canada and unfortunately I can not find L-Citrulline alone and all I can find is Citrulline Malate so I have bought this I bring this up because I did read a study that said that taking L Arginine HCl alone could increase the possibilities of heart attacks and by pairing L Arginine with L Citrulline deters this anomaly and helps to promote better bioavailability of NO in the blood system .....my question is do you know what would be a beneficial dosage of both ? ....Thank you
Daniel Hammer (2 years ago)
Hi John and thank you for your offer to promote Argi+ from Forever Living.  I just looked at your supplement facts for your product and I noticed that you leave out a key ingredient, which is the amino acid L-citrulline.  Is there any particular reason why this key amino acid is not part of your formulation?  Dan
John Shaw (2 years ago)
You could also use a product called Argi + from Forever Living Products; I'm on Facebook as John Shaw - Health With Aloe should you wish more information.
Daniel Hammer (2 years ago)
I apologize for the delay in answering your question as I just saw your post when the additional recommendation below showed up today in my inbox.  GNC is one method.  However, I would recommend ProArgi-9+ from Synergy Worldwide.  It is the only L-arginine supplement listed in the Physicians' Desk Reference.  And it is the only L-arginine supplement clinically proven in two important areas.  First, it produces higher amount of nitric oxide than L-arginine alone.  Second, it inhibits vascular inflammation.  You can purchase this product directly from Synergy Worldwide or if you need assistance you can call me directly at 1-800-966-3012 and I can help you obtain the product.
MSE. Dzirasa (2 years ago)
You can purchase the correct combination from GNC on line, or at a store near you. I'm sure you have GNC in Canada. They have both L-Citrulline 500mg and L-Arginine 500mg in one dose. You take one pill thrice a day for maximum support. Hope this helps. :)
Savage Beast (2 years ago)
thanks for this info... it was extremely healthful
Our Synergy Family (2 years ago)
I'm glad you found it helpful.  Please share this information with others.  Have a Blessed Day!  Dan
coscointernational (2 years ago)
If I drink beet juice in combination with an l citrulline supplement, will the nitrite/nitrate remove the nitric oxide that I get from the l citrulline? In other words, is it counter productive to drink beet juice with l citrulline? I was under the belief that taking both would increase my nitric oxide production. When is a good time to drink beet juice if I don't want to interfere with my nitric oxide production from the l citrulline? Thanks a lot!
coscointernational (2 years ago)
Oh, and I also take vitamin d before I workout as well. Forgot to add that in my long response.
coscointernational (2 years ago)
Thank you very much. So I will combine beet juice and l citrulline for better results! I have another question... What is your opinion on my current supplementation? I combine beet juice with l citrulline and glutamine about 30 mins before a workout. I also take ginkgo biloba, l tyrosine, chromium picolinate, d ribose powder, alpha lipoic acid, acetyl l carnitine, coenzyme q10, and CLA one hour before I workout, which is half an hour before I drink the beet juice and l citrulline. I notice that the latter combination helps with my mental focus without giving me the jittery feeling that I get from caffeine. I believe the reason is that the ginko biloba acts as a blood thinner as well as helps with cognitive function. Now the reason why I seperate them is because I believe that they will make their way in my blood stream by the time the best juice and l citrulline start expanding my blood vessels and my workout starts pumping blood into my muscles. I take bcaa while I workout and I drink coconut water. I mix the bcaa with glutamine. Right after I finish working out, I take zma and creatine, then wait half an hour before I take my homemade protein shake made with ground nuts (cashews, peanuts, pistachios, almonds, walnuts, pumpkin seeds, sunflower seeds) oats, milk, dates, rasins, raw honey and chocolate milk. I add cinnamon for an insulin spike. I learned that it's more important to get glycogen back into the muscles, and a high insulin spike can help get the carbs into the bloodstream quicker. I also take leucine, lysine, glutamine, vitamin c and calcium two hours after a meal. I eat papaya, kiwi and pineapple as well. Before bed, I have milk and egg protein with cottage cheese and berries. What I'm doing seems to be working so well that it's making me a bit concerned. I don't know what I'm doing right or what I'm doing wrong. I'm hoping that the results I'm seeing aren't some type of warning sign before something goes terribly bad. It's unreal the results I'm getting and the way I'm recovering. I don't understand chemistry so I might have accidentally created some typenof steroid or triggered some type of anabolic function. I'm afraid to share it with people because I don't want them to try it and have something bad happen to them because what I'm doing is just testing my theories and trying to be creative. Sorry for the very long response, and hopefully you have some kind of answer! Thanks again!
Daniel Hammer (2 years ago)
Hi and thank you for the question.  No, just the opposite will happen.  The l-citrulline will enable the endothelial pathway to help you create nitric oxide, which will boost your nitric oxide production and help you maintain it for a longer period of time.  This is what CirO2 and Neo40 do.  Even though they tell you the endothelial pathway is dysfunctional if you are over the age of 40, they still use it because they know the nitrate/nitrite pathway for the production of nitric oxide is short lived.  So they add L-citrulline to their product to get more nitric oxide production via the endothelial pathway that they tell you is dysfunction.  They are duplicate in what they tell people but that is what they are doing.  So combining both the beet juice with L-citrulline is going to give you better nitric oxide production over a longer period of time.  I hope this helps clarify this issue for you.  Have a Blessed Day!  Dan
John (2 years ago)
are there foods you can consume to enhance both for your body?
Sam D (1 year ago)
I read beets, for one. Google it.
frank1847 (2 years ago)
See this video on YouTube Dr Esselstyne . m v w .
R. J. U. (2 years ago)
Back again - Listening to your talk several times, putting aside my current experiences using L- Arginine, since the goal is cardiovascular health some things come into question about those doctors who poo poo'd the effectiveness of L- Arginine in people over 40yrs age and your references, rebuking those claims. My thoughts are this, if a person has plaque buildup in their arteries, or worse - the use of statins which coat the arteries, then the endothelium is coated and unexposed. So then the L-Arginine would be ineffective in that situation would it not? Especially since it's only a very thin layer. Unless - the plaque blocking it could be removed first, hence the use of the protocol given by Dr. L. Pauling, which was the use of Vitamin C & L - Lystine.
Daniel Hammer (2 years ago)
+Richard J. Urmano That's a great response on your blood pressure.  You mentioned a protocol from Dr. Pauling.  Do you have a link that you can send me so that I can see this?  That would be helpful to me in educating myself in this procedure.  Have a Blessed Day!  Dan
R. J. U. (2 years ago)
+Daniel Hammer Thanks Dan, I just ordered that book you mentioned. Your a blessing and I really appreciate your time and knowledge. I'm still on the Dr. L. Pauling proto-call, ramping up slowly, today for the full dose of C=3g L-ly=6g. spreading it across the day. I just took my BP and almost dropped my jaw, it has fallen 25 points in a day and is now at 126/62. It hasn't been there in years. In a week or so, if all goes well I'll try adding the L-Arginine / L- Citrulline into the mix and go after that tree stump! AND start dropping my BP meds!
Daniel Hammer (2 years ago)
+Richard J. Urmano Hi Richard.  Sorry to hear about your doctor's lack of understanding.  If you read the book NO More Heart Disease by Dr. Louis Ignarro he puts the amount of l-citrulline between 200 to 1000 mg.  It really depends on the quality of the l-citrulline.  Ideally free form and made from a bio fermentation process of non-GMO maize or corn.  Have a Blessed Evening! Dan
R. J. U. (2 years ago)
+Daniel Hammer Thank you Dan, my Doctor said that the statins coated my arteries, so he really doesn't know what's happening other than he gets a kickback from big pharma for every script he writes. In your talk you mentioned that there is a proper combination in the correct use of L- Arginine & L- Citrulline. I had heard that the L-Arginine dosage is 5G daily, but what is correct dosage for L-Citrulline? Thanks again. Rich
Daniel Hammer (2 years ago)
+Richard J. Urmano Hi Richard and thank you for your thoughts and comments.  The use of statins is not to coat the arteries.  Instead, statins work in the liver to disrupt the metabolic pathway for the creation of cholesterol.  Your liver creates the majority of your cholesterol since every cell membrane needs it to hold the membrane together.  The problem with statins is not only does it interfere with the liver's ability to create cholesterol (thus lowering cholesterol numbers) but it also interferes with the same metabolic pathway used to create CoQ10 which is a key energy source especially for the heart.  This is why congestive heart failure has risen with the use of statins.  The removal of plaque can be a function of high enough nitric oxide levels to initiate reparative mechanisms that over time will help heal this damage.  Also the use of vitamin K2 can help to reverse the calcification of the vascular system to return the endothelium into a health and function tissue.  I've seen research that supports the use of vitamin C in this process, but I've not seen research regarding L-lysine.  At least that is the amino acid I think you're referring to.  I hope this information is helpful.  Have a Blessed Day! Dan
Barry Blakeley (2 years ago)
I know it is spelled Arginine but it is pronounced AR-JE-NEEN
Adrian Ce-cat (2 years ago)
Hello Daniel. I've looked and I can not find and questions on this. Just to clarify. One of the ingredients in argipro 9 vitamin b pyridoxine hci. In this video you talk about the negatives of hci. Is there a difference between the hci's?
MarketTopcontent (2 years ago)
I used to take Arginine Infusion and would like to get back to supplementing and am considering ProArgi-9 as I can appreciate the differences pointed out. My question is can I(should I) also juice while taking ProArgi-9? I ask because I currently juice a mixture of beets/apples/celery to also help regulate my bp. The high beet root concentration was recommended. Can this safely be combined with ProArgi-9? Thx
Daniel Hammer (2 years ago)
+MarketTopcontent Hi and thank you for your comments.  I highly recommend ProArgi-9+ and I use it with all my clients.  Regarding your questions about combining it with a high beet root concentration there should be no issues.  However I would recommend keeping them separated by 4 to 6 hours.  Here's why.  The beet root is going to create nitric oxide through the nitrate/nitrite pathway.  This is a valid pathway for the creation of nitric oxide but it is a short lived pathway.  The key is long term production of nitric oxide to initiate reparation processes to your vascular system.  So if you do the beet juicing in the morning.  This will help increase your nitric oxide levels.  Then at lunch time or mid afternoon take a serving of ProArgi-9+.  This uses the L-arginine pathway through the endothelium and will help you maintain higher levels of nitric oxide over a longer period of time. This way you can augment the nitrate/nitrite pathway for the needed long term production of nitric oxide.  If you have questions about this then please call me at 1-800-966-3012.  And if you're wanting to order ProArgi-9+, then please also call and I can share with you the pricing I use with my clients.  Have a Blessed Day!  Dan
GizmoFromPizmo (2 years ago)
This is, honestly, the best and most thorough presentation I've ever heard on this subject - by far. The NOW brand of L-Arginine says that it is "Free Form". After listening to this video, I now understand that Free Form L-Arginine is not bound to other substances (like HCl - as in the video). I learned something :) Furthermore, I'm also supplementing with L-Citruline. I'm weaning myself off high blood pressure medication.
Daniel Hammer (2 years ago)
+GizmoFromPizmo Thank you for the kind comments and I'm glad this video was helpful to you.  It is amazing what Nitric Oxide Therapy can do to help people improve their cardiovascular health. It's choosing products that are high quality so that the endothelium can convert the right nutrients into nitric oxide.  Have a Blessed Day!  Dan
Rene Canuto (2 years ago)
Have you done much research on Dr Rainer Boger's Arginine Cardio?  It sounds better than Pro Argi 9 plus.  What have you got to say about Arginine Cardio?
Ron Wilmot (2 years ago)
I was diagnosed with a Calcium score of 800+. l arginine appears to be a product of several which may reverse Atherosclerosis. I buy 3 products in bulk from Bulk Supplements; L-Citrulline; D-Robose & L Arginine; mix them together taking 1 tsp each twice a day. K2 & Krill is also taken among many other quality vitamins. would the benefits be sufficient compared to ordering a single product that is more expensive than what I am using? Thank you
Daniel Hammer (2 years ago)
+Ron Wilmot Hi Ron and thank you for the question and information.  In looking at the information you sent me I see two issues.  One is your calcium levels and the other is cost for an effective nitric oxide therapy strategy.  I'm not sure how much K2 you're using but this would be the first step in helping to better control your calcium levels.  I would also look at combining the K2 with vitamin D3.  If you Google K2 and calcium you should find some peer reviewed studies that will help you with the amount.  Regarding the cost factor.  I'm not sure how much L-arginine you're taking.  5 grams is considered the therapeutic level for optimal nitric oxide production so you will have to do some math to find out which is more cost effective.  I've usually found that when you buy individual ingredients and then have to combine them at the same levels in a properly formulated product, there usually is no savings or at least not enough to justify having to take multiple sources.  I hope this helps.  Have a Blessed Day!  Dan
Kathy Bergman (2 years ago)
Hi Dan - I checked out the product you recommended but I was discouraged to see that everything has a flavor. Some of us are sensitive to additives. Can you tell me what form of arginine is safe --because the synergy website didn't list that either. That concerns me. Thank you for the informative video.
Christopher Allan (3 months ago)
Have you found a supplement to enhance your nitric oxide production?
Kathy Bergman (2 years ago)
+Daniel Hammer Thanks, Dan. So the pharmaceutical grade l-arginine isn't the HCL version? Also -- I've used the normal version from the health food store and it doesn't taste bad :) Maybe the pharmaceutical grade is different? Just trying to understand!
Daniel Hammer (2 years ago)
+Kathy Bergman Hi Kathy and thank you for your comments.  I'm not sure where you were looking on the Synergy website but they clearly disclose that they use pharmaceutical grade L-arginine which is derived from a bio fermentation process of non-GMO grain.  It's the purest form.  They also use the same process for their production of L-citrulline.  I do not know of any combination product that will not have some type of flavoring additive if it is in powder form and you mix it with water.  The reason is L-arginine by itself is pretty nasty in taste so you need a low-glycemic sweetening system to hide the taste.  Hopefully this information helps.  If you decide to use ProArgi-9+ from Synergy please remember that they have a 120 day money back guarantee of their product.  So you can try it and if the additives cause a sensitivity issue for you, you can then return it for a full product cost refund.  Just be aware they don't refund the shipping fee.  Have a Blessed Day!  Dan
dream ah (2 years ago)
i have used argi pro plus but, nothing realy happend and the product is chaged to little suger bags. i will try only a cheap brand of l arginine nextime
R. J. U. (2 years ago)
Started taking it and my blood pressure shot up 40 points so I stopped.
Daniel Hammer (2 years ago)
+Richard J. Urmano  Hi Richard, thank you for the follow up comments.  Please continue to keep me posted on your results as I'm always interested in natural ways that can be used to help address high blood pressure issues.  Have a Blessed Day! Dan
R. J. U. (2 years ago)
+Synergy Success Coaching Yes, I did start using freeze dried Beet Juice Power and my BP came down 10 points. But I also did more research and came across a brilliant posted talk from Dr. L. Pauling on using High Dosages of Vitamin C and L-Lysine. I started this yesterday and although my BP is elevated again, I am feeling much better, no chest pain. Still going to do the beet juice, I believe that things will improve. I'd like to retry the L-Arginine again at a later date after my BP drops back down. I'll give it a few weeks.
Our Synergy Family (2 years ago)
+Richard J. Urmano It's possible.  I noticed in one of your posts that you were going to use concentrated beet juice.  Did you use this?  And if you did what was your blood pressure response?  Have a Blessed Day! Dan
R. J. U. (2 years ago)
+Richard J. Urmano Just to follow up, I purchased a bottle from a known supplier and it had the same affect on my BP. It may be an interaction with my meds for high-BP.
R. J. U. (2 years ago)
Well, I tossed out the batch - but think it may be a safer choice to use concentrated beet juice for the No. effect  Also, I may try some L-Arginine in capsule form from a well known supplier, just to see if it's me or if that batch was contaminated.Mabe it came from China?
Cassie Bond (2 years ago)
So what is really odd about what you recommend on yourwebsite, which I found by googling your phone number, is the ProArgi product you recommend doesn't have any L-citrulline in it. Could you help me to understand why you are recommending this product when your video is all about the proper combination of L-arginine and L-citrulline? I am genuinely baffled.
Daniel Hammer (2 years ago)
+Cassie Bond Hi Cassie thank you for the comment about ProArgi-9+.  Your statement about ProArgi-9+ is not accurate.  If you look at the supplement facts and go down to the "Proprietary Blend" you will see L-citrulline listed as the third ingredient on the Grape formulation and the fourth ingredient on the Mixed Berry formulation.  As to why I recommend this product:  1.  It is the only L-arginine supplement listed in the Physicians' Desk Reference - 3 years in a row  2.  There are 262 verified quality assurance steps in the manufacturing of this produce so I know my clients are going to consistently get the ingredients on the label  3.  The L-arginine and L-citrulline are Pharmaceutical Grade where as most other products are Food Grade - big difference in absorption between the two grade levels  4.  This product is now "Clinically Proven" is two areas.  First, it produces higher levels of nitric oxide than L-arginine alone.  Second, and more important, it inhibits vascular inflammation, which is the major cause of plaque formation in the vascular system.  5.  I've seen some very remarkable results with this product.  I've clients that use this product who where sent home by the medical community to get their affairs in order that are now healthy adults either off their medications or have been able to reduce their medications and are now 3 and 4 years past the time the medical community told them they would not make it.  I could continue to give you more reasons but I think these 5 points helps you understand why I use and recommend this product to my clients.
Cassie Bond (2 years ago)
Oh I see the point.
nublackmusic (2 years ago)
Ok i watched the entire video but you did not recommend a product. For those of us suffering from heart disease who could drop dead at any min , we need good recommendations. we dont have the time or even the strength to do alot of research. your recommendation of a product to help those with very high blood pressure and weak hearts would be very much appreciated.
Daniel Hammer (2 years ago)
+nublackmusic Let me know if I can be of any further help to you in using this product to help address your cardiovascular concerns.  Have a Blessed Day!  Dan
nublackmusic (2 years ago)
+Daniel Hammer ok thanks. going over to amazon right now to order. Peace!
nublackmusic (2 years ago)
+Daniel Hammer ok thanks. going over to amazon right now to order. Peace!
Daniel Hammer (2 years ago)
+nublackmusic Hi and thank you for your question and feedback.  I purposely wanted this video to be an informational video.  However, in answer to your question I would recommend ProArgi-9+ from Synergy Worldwide.  This is the product that I use for all my clients.  It's the only L-arginine supplement listed in the Physicians' Desk Reference.  It's been listed for the last 3 years.  It's also the only "clinically proven" l-arginine supplement.  Here is a link to my most recent video on this product:  https://www.youtube.com/watch?v=wdyf_dJZer4  If you're interested in this product, then please call me directly at 1-800-966-3012 or email me at dan@agingnomore.com and I can provide you with a price quote for ProArgi-9+.  Have a Blessed Day!  Dan
John Yarbrough (2 years ago)
Its very strange I have this effect with Ace inhibitors, ARB medications, yohombie, L Arginine, and the most recent product I tried which is Source Naturals L-Citrulline, 1000mg. My blood pressure lowers and i'm healthy in other areas if you know what I mean but anything that relaxes my blood vessels has a psychiatric effect and its very strange. Hours of google searches and conversations with doctors I am told that I'm a rare breed. I wonder if there is an underlining condition or I'm just going about it all wrong, I've seen you in a documentary before and you seem very knowledgeable and maybe you have some insight.
John Yarbrough (2 years ago)
Could anyone explain to me why L-Arginine would make me anxious?
Daniel Hammer (2 years ago)
+John Yarbrough Hi John and thank you for the question.  Before I can give you a complete answer, my question back to you would be what form of L-arginine are you using.  If it's pharmaceutical grade I've never seen this symptom.  If it is a lessor grade or if it's attached to either HCl or AKG then the symptom is most likely due to the carrier molecule they are using to boost absorption.  If you send back to me the exact product that you're using then I'll try to investigate for you.  Have a Blessed Day!  Dan
Vitoamiibo (2 years ago)
CAN SOMEBODY PLEASE TELL ME IF I SHOULD TAKE IT ON NON-TRAINING DAYS?
Christopher Allan (3 months ago)
Your body ALWAYS needs nitric oxide to deliver blood, which carries oxygen and nutrients to each of your 75 trillion cells, to keeps you alive. You can live 5 minutes without oxygen but only 5 SECONDS without nitric oxide. Your body produces it always. But as we get older, our bodies produce less of it because as we age, our endothelium cells diminish causing less oxygen and nutrients to get to each cell for optimum health. The average person loses about 50% of nitric oxide production by the age of 40. It becomes more imperative to supplement nitric oxide production as we age. How do you supplement nitric oxide production?
Yannick Long-Dupont (2 years ago)
very great video , do you know the proper amount of each, i would say half dose of each one is recommanded. you talk about pomegrnate wich i dont know, but i know about beet
Daniel Hammer (2 years ago)
Thank you for the question and the answer is Yes and No.  If you're eating watermelon then your getting L-citrulline.  However, the largest amount (about 60%) of the L-citrulline in watermelon is contained in the rind portion that most people throw away.  I don't know about the strawberries and cherries but pomegranate enhanced the enzymatic activity of the endothelium to help produce higher levels of nitric oxide.  If you are supplementing with L-arginine then I would also suggest supplementing with L-citrulline and then adding the pomegranate as a way to boost both.  Have a Blessed Day!  Dan
Daniel Hammer (2 years ago)
+Vitoamiibo Thank you for your question.  Yes you can take this product everyday.  You do not need to cycle on and off like other amino acid blends.  This product is designed to optimize the ability of the endothelium to enhance its nitric oxide production for improved blood flow.  This will aid you in your workouts but also in your recovery.  It is "clinically proven" to produce higher levels of nitric oxide than L-arginine alone.  If you are using this product, or if you are considering using this product, then daily use is both recommended and beneficial.  If you have any questions, then please call me directly at 1-800-966-3012.  And if you want to order this product just call me directly.  Have a Blessed Day! Dan
juan cruz (2 years ago)
L cetruline and L arginine really good stuff very good. 100% bad ass L cetruline very good for making babies.
Espy (2 years ago)
Be careful you don't get totally healthy and diabetes free Willow Dawn you may make this "..... " look stupid and definitely be of no more profit to the medical industry.. By the way cool Pharmaceutical advert only posted for promotion Mr Dan. Do you enjoy being a big Pharma puppet ? Oh they call them employees these days ? Seems you have a lot of trusting and happy viewers here/potential customers. Good Job. Have a Blessed Day Danny boy.
Daniel Hammer (2 years ago)
+Espy Hi Espy and thank you for the gracious apology.  I'm sorry for the loss of your mom.  They are so important to our lives especially when their deaths could have been prevented.  I pray you will find the ability to forgive and then harness your passion and energy into helping others find natural solutions to their health challenges so that you can spare others the pain you experienced.  Have a Blessed Day! Dan
Espy (2 years ago)
If that truly is the case Dan, please forgive my ignorance and statement. I have an attitude problem for sure. I do realize it but it is directed only toward the Medical/pharmaceutical industry. I lost my mother to prescription drug addiction and I know about the industries total greed based agendas and lies. Been focusing a lot on it lately and totally misinterpreted your presentation. Peace..
Daniel Hammer (2 years ago)
+Espy Hi Espy and thank you for your judgmental attitude.  I'm a firm believer in Nitric Oxide Therapy and how it can be a natural way to improve cardiovascular health.  None of this has to do with the pharmaceutical industry since these are nutritional supplements.  So I can't be their puppet.  And I don't mind educating people in this area so that they can make good decision on how they want to address their health challenges.  Thank you for the Blessing and may you have a Blessed Day as you serve others.  Dan
Peter (2 years ago)
Thank You for this very important information. Once again you have answered my questions on this subject quite well. After having chest pains and palpitations and finally having and scan of my heart it was determined and showed calcium deposits in the arteries of my heart. In wanting to avoid the normal procedures for the treatment of this condition I came across Dr Ignarro Noble Peace award-winning articles for his work in this area. In following this path, it led me to ProArgi-9 Plus and your web site. You have been very informative and helpful. I feel I am on the right path. The proof is that I no longer experience the same symptoms, and I will have to have another heart scan to look at the results, but I am not sure if I will have another scan. Exercise, proper diet and proper information are my goals. Thank You Very much
Daniel Hammer (2 years ago)
+cycap1 Your welcome and I'm glad the information on this video and my website have been helpful to you.  I'm a firm believer in the power of nitric oxide therapy to naturally address cardiovascular concerns to help restore your vascular health.  And of all the nitric oxide products on the market, ProArgi-9+ is the one I use with my clients.  I wanted the above video to be free of any product endorsements but when you look at all the products out there ProArgi-9+ is "clinically proven" to produce higher levels of nitric oxide than L-arginine alone.  And it inhibits the oxidation of LDL cholesterol, which causes most of the inflammation of the vascular system that can lead to plaque formation.  I just recently posted a new video on this product https://www.youtube.com/watch?v=wdyf_dJZer4 to help others understand how well designed this product is for helping create the needed nitric oxide.  Thank you for sharing your situation.  Have a Blessed Day! Dan
goldphysh (2 years ago)
What about "L-Arginine HCl " is that the same thing?
Daniel Hammer (2 years ago)
+goldphysh Thank you for your question.  I would not recommend L-arginine HCl for a couple of reasons.  Typically this is a synthetic L-arginine.  Not always but most of the time.  Second, HCl is hydrochloride and is used as a carrier molecule to boost absorption.  When cleaved off in the bloodstream it can lower potassium levels.  Potassium is need for muscle relaxation and this can have a negative effect on heart muscle function.  There are too many other good L-arginine products to even consider using this.  My recommendation is ProArgi-9+ from Synergy Worldwide.  It is the only L-arginine supplement clinically proven to be more effective in the product of nitric oxide then l-arginine alone.  If you have further questions in this area please email me at dan@agingnomore.com or call me directly at 1-800-966-3012.  Have a Blessed Day!  Dan
Trish Truitt (2 years ago)
Excellent info. Thank you.
Daniel Hammer (2 years ago)
+Mike G HI Mike and thank you for your question about Arginine Infusion.  I don't like to criticize other products so I'll make just a few comments on Arginine Infusion.  The vitamin K they use is K1 not K2.  This is a big difference.  Vitamin K1 has no real benefits to the cardiovascular system.  In is inexpensive to use but does nothing to help regulate calcium levels in the bloodstream.  Vitamin K2 will and since the production of nitric oxide through the L-arginine pathway is a calcium dependent reaction, this is an important distinction.  I also question the use of AstraGin to help boost absorption levels.  It usually means that the bioavailability of the other nutrients are lacking.  And I'm not sure of the sourcing for L-arginine and L-citrulline although they seem to be free form which is good.  I use a product called ProArgi-9+ with my clients because it is "clinically proven" in this area of nitric oxide therapy.  Here is a video on ProArgi-9+ and how they've designed this product https://www.youtube.com/watch?v=wdyf_dJZer4  Hopefully this information is helpful to you.  Have a Blessed Day! Dan
Mike G (2 years ago)
+Daniel Hammer What is your opinion of Aginine Infusion? I have been using it primarily because it combines L-Arginine with the L- Citriline, as Iv also read elsewhere of the importance of these two together. It also contains vitamin K, D, B12 and resveratrol I believe. Thanks
Daniel Hammer (2 years ago)
+Trish Truitt Thanks for tweeting it.  The L-arginine in ProArgi-9+ is both free-form and pharmaceutical grade.  So it's the purest and most potent form of L-arginine.  It's produce from a bio-fermentation process of non-GMO maize or corn.  Dan
Trish Truitt (2 years ago)
I've already tweeted it and will do more. BTW: The Arginine I used before was Arginine HCI - which I assume is the synthetic kind. Does yours have free-form or AKG form?
Daniel Hammer (2 years ago)
+Trish Truitt I'm glad you found value in the information.  Please share this video with others so that we can help as many people as possible understand the value of nitric oxide therapy to naturally address cardiovascular concerns.  Have a Blessed Day!  Dan
Christine Thomas (2 years ago)
That was great info, thank you for that, especially when not from a medical background :) On the picture with all the different products with L-Arginine, I didn't see Argi + by Forever Living Products, so I was wondering if you know of it, it has all it needs working in synergy and was endorsed by Dr Murad, one of the 3 laureates for the Nobel Prize in Medicine. I have been taking it for a few months now and my blood pressure has gone down to what it used to be like in my twenties!! My friend's dad has also been taking it and the doc has had to reduce the meds he was taking for his cholesterol and his memory has improved... really delighted with the results, but now I understand much better why it is working!! Thank you and God bless :)
Daniel Hammer (2 years ago)
+Christine Thomas Hi and thank you for your comments.  Yes I'm familiar with this product and while I believe there are some better formulated products in this area I'm glad to hear that it is working for you and your friend's dad.  If this is the case then I'd stick with it since you're seeing results.  I'm glad you found the information in the video helpful.  Please share it with others so that we can help people understand the power of nitric oxide therapy to naturally address cardiovascular concerns.  Have a Blessed Day! Dan
MrSixunder (2 years ago)
Good video! I took L arginine three years ago but failed to also take citrulline. I didn't notice any difference due to my own fault. Recently I was about to throw out my aging bottles of L arginine and I decide to revisit the web to see why I took it. After reading much more on the subject I decided to buy some citrulline and noticed a huge , huge difference. My heart pvcs have greatly reduced and my breathing is much better. Glad I didn't just throw out the old L arginine! Hammer time!
Daniel Hammer (2 years ago)
+MrSixunder Hi MrSixunder!  Thank you for the comments and helping others understand that it is the combination of L-arginine and L-citrulline that makes the difference.  By itself the increase in nitric oxide via L-arginine is short lived but when you add the L-citrulline to help recycle this process you can get higher production of nitric oxide that also lasts longer so that you can see noticeable improvements.  There are other ingredients that can also help enhance the production of nitric oxide.  I personally like the design of ProArgi-9+ from Synergy Worldwide.  They've done peer reviewed clinically studies on this product and clinically proven that it is more effective in the creation of nitric oxide then just l-arginine alone.  When you're done with your current supply you might want to check out this product.  If you've any questions on it then directly email me at dan@agingnomore.com  Have a Blessed Day! Dan
dat nguyen (2 years ago)
That's a very informative video. I never really thought about the age factor in the synthesis of L-Arginine. So, what do you think about using citrulline to produce, and maintain higher level of arginine plasma within the blood? Since the kidney does synthesize citulline to arginine. I think that regardless of the matter, these two amino acids are two of my favorites.
Daniel Hammer (2 years ago)
+dat nguyen Hi and thank you for your comments.  L-citrulline is an excellent choice because the body can convert it to L-arginine for the creation of nitric oxide thru the endothelial pathway.  In fact, I didn't catch this when I did my video The Truth About L-arginine but companies like Neo40 use L-citrulline in their products to boost nitric oxide levels because of the inefficiency of the nitrite/nitrate pathway.  What I failed to point out is that the conversion of L-citrulline to L-arginine then goes down the same pathway that Neo40 is telling you is ineffective if your over the age of 40.  It sounds like I need to do another video called The Truth About L-Citrulline to expose this misinformation on their part and help people understand that this amino acid is vitally important.  Have a Blessed Day!  Dan
Anthony Pike (2 years ago)
An Excellent presentation! One of the best and most informative videos on YouTube. Thank you.
Daniel Hammer (2 years ago)
+Anthony Pike Thank you Anthony for your kind comments.  I'm glad you found great value in the information.  Please share this video with others so that we can help people better understand the power of nitric oxide therapy to address cardiovascular concerns.  Have a Blessed Day! Dan
Glenn Carr (3 years ago)
From an n=1 perspective I have been taking L-arginine and L-citrulline together (around 1 tsp per day combined - a 100g bag of arginine with 25g of citrulline). The results have been somewhat unexpected but very encouraging. At 41 years of age I fall into this category you spoke about in the video so should not expect any effect. From a personal perspective I have noticed a significant increase in 'morning glory' if you get where I am coming from! Not just that but through the day too I have noticed significant changes to the blood flow to a certain appendage. This was an unexpected result but leaves me the question of just how important this change is to the body overall. A supplement that can cause reversal of erectile dysfunction (not that I thought I had any) through improving blood flow around the body has very significant implications for health. Personally I am pretty sold on the combination and I can pretty much state that this is not just some placebo effect as I have tried several supplements and found most don't deliver their claims. Arginine/citrulline works for me, I have no doubt about that. The effects are not immediate but happen over an extended period of time - my side effect has become more frequent and even happens in the day! Not as bad as I used to get as a teenager but at only 6 weeks in and on a pretty low dose (the total of 125g combined I bought still has around two weeks worth left). This translates to a dose of only around 2g per day so is pretty low yet has still given me some pretty impressive results. I intend doubling the dose (around 1tsb morning and night) to increase the amount of time NO production happens to twice a day. I don't expect to be pole vaulting any time soon but based on the story so far expect that this can only further improve my circulation. The great part is that the production of NO in myself is likely dropping back to base levels yet the effect on my blood flow seems to be unrelated to this. The only reason I can deduce from this is that the changes I'm seeing aren't just while under the influence of these amino acids but a permanent change to my overall blood flow. The time taken for things to improve also supports the notion that the effects aren't only there while the amino acid is present. Taking them repeatedly has simply created some long term repair of my overall blood flow to healthy levels I experienced at a younger age. This stuff is no flash in the pan supplement of the day but a really beneficial combination that (at least for me) has worked very significantly.
Daniel Hammer (2 years ago)
+Adrian Cecato Hi I saw your question to Glenn.  The product I would recommend is ProArgi-9+ from Synergy Worldwide.  It's been in the Physicians' Desk Reference for 3 years straight and is the only "clinically proven" l-arginine supplement.  This link will give you more information is you decide to check it out  http://danhammerhealth.com/the-proargi-9-difference/  Have a Blessed Day!  Dan
Glenn Carr (2 years ago)
+Adrian Cecato No specific brand, I got mine from Ebay.
Adrian Ce-cat (2 years ago)
sorry +Glenn Carr
Adrian Ce-cat (2 years ago)
Hello +Glenn car what product brand do you take?
anikoustos2 (3 years ago)
how about arginine and herpes outbreaks?
Daniel Hammer (3 years ago)
+anikoustos2 That's a great question.  From my experience this is usually not an issue unless a person is consuming an excessive amount of L-arginine.  An excessive amount would be 20 grams or more per day.  If a person is sensitive in this area, then the best precaution is to also consume L-lysine, which inhibits the expression of this virus.  Don't take both L-arginine and L-lysine at the same time because they both compete for the same receptor sites.  I would keep them separated by at least 6 hours.  Usually 500 mg to 100o mg per day is good for prevention.  And 2000 mg  per day is good to help overcome an outbreak.  Have a Blessed Day!  Dan
dmanofalltime23 (3 years ago)
I would like more info about joining your team.
Daniel Hammer (3 years ago)
+dmanofalltime23 Oops!  I put one to many "n" in the email address.  It is dan@agingnomore.com Sorry about that.  Have a Blessed Day! Dan
dmanofalltime23 (3 years ago)
+Daniel Hammer I tried to email you. Is the email correct?
Daniel Hammer (3 years ago)
+dmanofalltime23 Hi and thank you for your interest in joining Our Team.  Please contact me directly at 1-800-966-3012 or email me at dan@agingnnomore.com Please let me know where you are located.  Once I have this information we can set up a time to talk.  Have a Blessed Day! Dan
Joe Schmoe (3 years ago)
Another factor in heart disease is the consumption of ruined essential fatty acids, EFA's. EFA's line the endothelium. Omega 6 and omega 3 are EFA's. Omega 6 lines the endothelium. Most of the omega 6 consumed today is ruined by processing and heating. Virtually all vegetable cooking oils are processed oils such as corn, soy and canola. Most breads and baked goods are made with it too. Virtually anything found on a grocery shelf that contains these oils are ruined. Cholesterol transports omega 6 via a lipoprotein. The cholesterol combines with the omega 6 and is called cholesterol esters. It is important to replace damaged omega 6 with unprocessed unheated omega 6. A good source is sunflower oil. It is high in omega 6 (65%). A teaspoon or 2 a day is all that is needed, but it must be virgin cold pressed unrefined and unheated. It can be obtained in health food stores or on the internet. Amino acids alone is not the answer.
MSE. Dzirasa (2 years ago)
Is raw/uncooked extra virgin olive oil good for the endothelium?
Phoenix25 (3 years ago)
I trully appreciate the information you have provided in this video. I have learned a lot in this one vid more than any other vid! I will continue to take NO and recommend to many others to take it to help their hearts. Thank you Dan!
Christopher Allan (3 months ago)
What product do you use to enhance nitric oxide production?
Phoenix25 (3 years ago)
+Daniel Hammer I will def share this vid! Thank you and be Blessed!
Daniel Hammer (3 years ago)
+Randy Figueroa Your welcome and thank you for the kind comments.  There are so many people who could experience tremendous cardiovascular improvements if they just knew how to apply this information.  So please share this video with others so that we can help them enjoy a healthier life.  Have a Blessed Day! Dan
protovu (3 years ago)
Thank you for this comprehensive exposition.
nathaniel ackley (3 years ago)
I take a combination of 5000mg of l-Arginine and 1600 of L-Citruline this seems to work for me. love the video. its very true you need a combination and a good one to keep Nitric Oxide in the system.
bobluhrs (3 years ago)
I am wondering if what I take is ok, or should be changed. I take L-arginine in the form: Arginine Ethyl Ester. I combine it with Citrulline Malate, 3:1. (3 arginine to one citrulline). Arginine ethyl ester is said to enter bloodstream with less losses in the gut than either straight Arginine, and even better than Arginine AKG (alpha ketoglutarate). The ethyl ester carries it quickly through the small intestine to the blood, or words to that effect. Citrulline plus mallic acid (citrulline malate) is said to enhance the effectiveness of L-Citrulline by acting on or after the Krebs cycle, but I don't have much data on this. One thing the 'malate' does is tastes less nasty than straight L-citrulline, which by itself is quite noxious. Should I change to straight L-Arginine/L-citrulline, or is my current formula ok? GREAT video! Many thanks. I wondered about the Hopkins-arginine heart study and why it backfired. It appears your HCL explanation fits perfectly. I am a great fan of Dr. Joe Prendergast and could not believe he could be so wrong over 20 years and 7000 patients! Apparently he wasn't wrong at all.
Erol Yildiz (3 years ago)
Hi Dan, First of all thank you for this wonderful video which is incredibly easy to understand even the subject is hard. Is it a good idea to use arginine and citrulline with b6, b12 and folic acid to decrease high homosystein levels? By the way I trust in solgar brand for many years and it has arginine but doesn't have citrulline supplement, makes me a bit suspicious, do you have any idea why? Thanks again for sharing your work with public, best wishes for you.
Daniel Hammer (3 years ago)
+Erol Yildiz Hi Erol!  Thank you for the kind comments.  I'm glad you found the video helpful.  Yes, by combining B6, B12 and Folic Acid you will see a benefit.  Also, vitamin K2 and pomegranate fruit concentrate are also two other good nutrients to enhance nitric oxide production.  I don't have an opinion on solgar but if you're looking for what the medical profession considers the best of all the L-arginine supplements then I'd recommend ProArgi-9+ from Synergy Worldwide.  Have a Blessed Day!  Dan
Willow Dawn (3 years ago)
Excuse me, I'm 53 years old and I take L-Arginine 3 times a day, and have lost 5 pounds in a week and my blood pressure is down, and my diabetes type 2 is way under control... wow. works for me!
Vincent Stewart (11 months ago)
Willow Dawn íó
Marie tan (2 years ago)
+Willow Dawn amazing
RemyLebeau1105 (2 years ago)
Thanks Dan, God bless. 
Daniel Hammer (2 years ago)
+RemyLebeau1105 Hi RemyLebeau!  I'm not sure which product that Willow Dawn is using but I would recommend looking at ProArgi-9+ from Synergy Worldwide,  It's the only one recognized by the medical community since it is listed in the Physicians' Desk Reference and just recently it was clinically proven to be more effective in their creation of nitric oxide than L-arginine alone.  If you have questions about this product, then either call me 1-800-966-3012 or email me at dan@agingnomore.com  Have a Blessed Day! Dan
RM chain (3 years ago)
Excellent information. Question. Can L-Arginine in any amount affect kidney or liver function? Thanks RM
carla obus (3 years ago)
+RM chain _?_
carla obus (3 years ago)
+RM chain _?_
Devikah (3 years ago)
This is a wonderfully informative video.  Thank you for that. My dad is taking this brand: http://www.swansonvitamins.com/swanson-ultra-ajipure-l-arginine-sustained-release-tab-1000-mg-90-tabs .  It's pharmaceutical grade and time released.  Adding L-citrulline will optimize the ability of the endothelium to create nitric oxide, is what I got from the video. Since my dad is pretty loyal to Swanson products, I'll get him a bottle of this... http://www.swansonvitamins.com/swanson-superior-herbs-pharmaceutical-grade-l-citrulline-850-mg-60-veg-caps ... for him to take with the L-arginine. Thanks again.
john Lynn (1 year ago)
Devikah
BrunoAngelico (3 years ago)
Synthetic Arginine supplements are extremely dangerous because they don't create Nitric Oxide as promoted but Nitric Acid which is very destructive in the human body. This video missed that explanation. One Arginine study was stopped because instead of helping people sensitive to heart attacks it enhanced it because of that internal chemical reaction in the human body. L Arginine can only be safely absorbed as supplements thru food.  People need to understand that what is tested in a lab glass tube has nothing to do with the actual internal chemistry of the human body.
BrunoAngelico (3 years ago)
+Daniel Hammer I watched your video. My comment is not misleading at all. Dr Jerry Tennant who is also an MD who did extensive research on nutrition for decades and was also part of various studies fully agrees with me. Do your research. As a professional athlete I tested L arginnine years ago and the results were zero, null ! I even noticed a serious decreased of energy, with weird joints and muscles pain after 2 weeks of use. Pharmaceutical Arginine is complete crap as you say, fermentation of glucose ( and GMO corn, even worse) raising acidity in the body, basically acting as a precursor of alcohol getting in the blood and cells. I'm way older now and have more energy than ever getting real nitric oxide from beets and Arginine from food like herrings with L citrulline from watermelon etc. That applies also to synthetic Vitamin C supplements too, completely unstable and useless!  I don't know anybody in the world at my age that can accomplish the level of stunts having the physicality I have. Even Jackie Chan slowed down few years ago because of pain and recovery time. And this is only due to perfect and balanced nutrition from real "live" food, herbs and plants. 98% of synthetic supplements are completely useless and toxic. They have no life force as "electrical voltage" most molecules are insoluble or un-absorbable by the human body chemistry. God's creation was perfect. Man's creation from manipulated, synthetized and processed food or supplements doesn't work or have major dangerous side effects. .
Daniel Hammer (3 years ago)
+BrunoAngelico Hi BrunoAngelico!  I've left your comment up for a couple of reasons.  First off, arginine supplements whether they be synthetic or natural do not produce nitric acid.  You will not be able to produce any research to defend your statement.  Second, you must not have watched my video because we discussed the study you refer to in your statement.  It is the John Hopkins study and the problem doesn't center on the synthetic L-arginine but the carrier molecule they used to boost absorption.  That was HCl hydrochloride which lowers potassium levels.  And the companies that use pharmaceutical grade L-arginine use a bio fermentation process of glucose or maize to produce a natural L-arginine.  Just some clarification to your misleading statements.  Have a Blessed Day! Dan
Chuck Olearain (3 years ago)
Don't take l-arginine if you are HPV positive. There should be a warning on the lable.
Christopher Allan (3 months ago)
Chuck Olearain This is why I take NITRO EXTREME!
Bill Sanders (3 years ago)
+Chuck Olearain - I believe Dan Hammer answered this objection above regarding herpes. That's a great question.  From my experience this is usually not an issue unless a person is consuming an excessive amount of L-arginine.  An excessive amount would be 20 grams or more per day.  If a person is sensitive in this area, then the best precaution is to also consume L-lysine, which inhibits the expression of this virus.  Don't take both L-arginine and L-lysine at the same time because they both compete for the same receptor sites.  I would keep them separated by at least 6 hours.  Usually 500 mg to 100o mg per day is good for prevention.  And 2000 mg  per day is good to help overcome an outbreak.  Have a Blessed Day!  Dan
carla obus (3 years ago)
+Chuck Olearain _?_
carla obus (3 years ago)
+Chuck Olearain _?_
maddux86 (3 years ago)
awesome  and informative! 
Daniel Hammer (3 years ago)
Thank you and I'm glad it has been helpful to you.  Have a Blessed Day!  Dan
zenpiper (3 years ago)
Dosage info would have been helpful. How much to take? 50mgs or 5 grams?
zenpiper (3 years ago)
Thanks a lot.  I was eventually able to find similar data on a website.  Cheers.
Daniel Hammer (3 years ago)
Thank you for the question.  If you read the book NO More Heart Disease by Dr. Louis J. Ignarro, who won a Nobel Prize in Medicine for his research in this area, he would say 4-5 grams of L-arginine and 200 to 1000 mg of L-citrulline.  I hope this helps you.  Have a Blessed Day!  Dan
Irwin Garcia (3 years ago)
you mentioned the proper combation of l- arginine and l- citrulline. What is the proper combation? you also mentioned the quality and pureit  of the l- arginine and l-citrulline. What the purest of and best quality l- arginine and l-citrulline. thanks for the info 
Magnus Johanson (7 months ago)
You do not want to combine Citruline but instead use Glutamine. There is a huge misconception about this because it is cheaper to use citruline and thus promoted by factories. .
Pietrad washere (3 years ago)
Many thanks for your informative video.  However, my research has come up with cautions about using L-Arginine when one has Glaucoma - which I have.  What is your take on that?
Daniel Hammer (3 years ago)
Thank you for your kind comments on the video.  I did some research on your question about Glaucoma and L-arginine.  I would assume that it is in relationship to nitric oxide production.  While I only did a quick search it seems that the older studies are negative towards nitric oxide and glaucoma but the more recent studies are positive in seeing nitric oxide as beneficial in restore improved blood flow which then helps to reduce pressure.  Here are two more recent studies reviewing this area: http://www.ncbi.nlm.nih.gov/pubmed/17420369  http://www.ncbi.nlm.nih.gov/pubmed/18543682 If you decide to use L-arginine you need to combine is with other key ingredients because it is the long term production of higher levels of nitric oxide that help to initiate reparative mechanisms to heal damage done to the endothelium, which in turn helps to improve blood flow.  With my clients I always start conservatively and gradually build up the amount they are using so that we can find what's best for them.  Have a Blessed Day!  Dan
Jerry Bruton (3 years ago)
I guess the question is should I consider this video of any merit, given the nitrate pathway for adults over the age  of 40 is a more effective pathway   advocated by Dr. Nathan Bryan of the School of Medicine at the University of Texas Health Science Center at Houston.  Dr Ferid Murad at the same institution, and a co-winner of the 1998 Nobel Prize on Nitric Oxide recruited Dr. Bryan.  Dr. Bryan explains the decline in nitric oxide production due to the increasing dysfunction of the L-aginine pathway with age.  So does it make sense to supplement a substrate to a declining pathway?  I prefer to use a pathway that does not decline with age given I'm 66 years ago and uses vegetables  rather than some manufactured product.  
Jerry Bruton (2 years ago)
+Daniel Hammer Thanks for the comments.
Jerry Bruton (2 years ago)
+gaastra12 It is obvious you do not understand the meaning increasing dysfunction of the L-arginine pathway. I can assume you lack the understanding of a negative slope of the Arginine pathway due to aging does not mean zero production of nitric oxide. I do follow the rule when someone makes a comment concern the source. I understand your issue. Jealous of a person in his middle 60s with the physique of a thirty-year-old. And I have an MBA from the University Chicago Booth School of Business, ranked fourth in the nation.
Daniel Hammer (2 years ago)
+gaastra12 While I don't want those who comment to call others names, you are correct.  Dr. Nathan Bryan's inclusion of L-citrulline is there for a reason.  Both the L-arginine and nitrate - nitrite pathway are valid pathways for the initial creation of nitric oxide.  However, there are both short lived.  You must include L-citrulline to boost nitric oxide production and extend its production over a longer period of time.  And as you've pointed out, the body converts L-citrulline to L-arginine and then goes down the same metabolic pathway that Dr. Bryan is telling people is ineffective if you are over the age of 40.  Thanks for sharing and have a Blessed Day!  Dan
peacock821 (3 years ago)
Dan, so what products contain the correct formulation of L-Arginine and L-Citrulline?
Amoreena51 (3 years ago)
Thank you so much for this thorough tutorial which will help me in making an informed decision
Daniel Hammer (3 years ago)
Thank you for your comment and I'm glad this video and the information it contained was helpful to you.
Michael R. Wright (3 years ago)
Wow! Incredible and awesome sir! Thanks.
Daniel Hammer (3 years ago)
+Michael R. Wright You're welcome Michael.  Have a Blessed Evening! Dan
Michael R. Wright (3 years ago)
+Daniel Hammer Love going back to this and reading this awesome and amazing information. Thanks again!
Daniel Hammer (3 years ago)
Your welcome!  I'm glad the information was helpful to you.
bomasol (3 years ago)
Daniel.  What are your thoughts and experiences of taking ProArgi9 while also taking Warfarin blood thinner?    
Daniel Hammer (3 years ago)
+bomasol Hi and thank you for the additional questions concerning K1 and K2.  Here is a link to an article that I think will be very helpful to you in understanding the difference between the two.  They are major:   http://chriskresser.com/vitamin-k2-the-missing-nutrient  Regarding use of ProArgi-9 Plus for your Mum.  My Mom is 87 and I give it to her everyday.  While she shows signs of aging they are significantly less than those in her same age category and she has no cardiovascular health issues.  As ProArgi-9 Plus nourishes the endothelium for improved nitric oxide production your Mum should see improved blood flow.  From my experience this would help her address some of the health issues she is facing.  While I've not been 100% successful with everyone of my clients I've seen some very significant improvement with those with congestive heart failure, my uncle being one of them.  In the High Desert Heart Institute Study that use ProArgi-9 Plus with 33 congestive heart failure patients who were all medically and pharmaceutically maxed out, they had no issue with any drug interaction.  Here is a link to an overview of that study:  http://cardiovascularwellnesschicago.com/education/hdhi-study/  If you listen to the interview with Dr. Siva (towards the end of the page) he actually addresses this issue of vitamin K during the interview.  I hope this provides you with the additional information you need to make the decision on what's best for your Mum.  Have a Blessed Day!  Dan
bomasol (3 years ago)
+Daniel Hammer  Danial.  Did some quick reading and it appears K2 is made from K1. Correct?  Looks like there are a few forms of K2 even (e.g. MK-8 and MK-9 ).     Anyway just to be more complete  I am contemplating  getting some of your Proargi 9 for my 91 year old mum who is diagnosed with COPD and congestive heart failure.   Se has bouts of swelling in her legs and Pleura Edema.   She is still walking around a bit but tires and gets out of breath quickly  (going 20 ft or so).   Her complete daily medication  is 2 mg  Warfarin,  40 mg Furosemide, 2.5 mg Bisolprolol, 80 mg Diovan.    Do you see any downside on administering your Proargi 9 on top of above dosages??  Appreciate your response. 
Daniel Hammer (3 years ago)
Hi Bomasol!  Thank you for your question.  Unlike some of the Nitric Oxide supplements that use vitamin K1 which can have a potential interaction with Warfarin, ProArgi-9 Plus uses vitamin K2, which acts completely different from K1.  Vitamin K2 has no know interaction with Warfarin and actually helps regulate calcium levels in the blood stream for better optimization of nitric oxide production.  When the High Desert Heart Institute used ProArgi-9 Plus in the 2009 study they had no concern about ProArgi-9 Plus and any of the drugs their patients were on.  Here is a direct quote off of the Synergy Worldwide website as it regards your question: ProArgi-9+ contains vitamin K—can I take it if I'm also taking blood thinners? With the prescribing doctor's approvals, ProArgi-9+ could possibly be taken along with blood thinners. While l-arginine does not directly affect blood clotting to any great extent, it may have an indirect beneficial effect through its actions in supporting vascular health. ProArgi-9+ contains vitamin K, which some sources have said needs to be limited while on the prescription blood thinner Coumadin (warfarin). Other sources maintain that vitamin K does not need to be limited, but intake needs to be consistent. Additionally, the form of vitamin K in ProArgi-9+ is K2, which does not have the same degree of potential Coumadin interactions as K1. As a general precaution, a person on Coumadin should consult with a qualified health care provider before adding any new natural supplement to their diet. When a new supplement is added, the doctor can keep a closer eye on monthly INR/prothombin time results (a test used to measure blood clotting) to ensure that they stay within a safe range. Why does ProArgi-9+ contains vitamin K2 instead of K1? Although vitamin K1 provides many of the benefits attributed to vitamin K, for optimal benefits, vitamin K2 is considered a superior choice. Vitamin K2 is a collective term for a group of vitamin K compounds called menaquinones. Studies have shown vitamin K2 to be more bioavailable and more efficacious in supporting bone mineral density. Studies on the effects of vitamin K on cardiovascular health show that vitamin K2 significantly improves arterial and cardiovascular health, while vitamin K1 has no effect at all. Vitamin K2 activates the vitamin K-dependent protein Matrix Gla-Protein (MGP), which plays an important role in preventing calcium from depositing in the arteries. I hope this additional information is helpful to you. Have a Blessed Day!  Dan
gman57op (3 years ago)
for those of you who want to increase NO2 just eat more protein and stack amino acids (cellucor watermelon flavor is my favorite. but at that age just take testosterone update I FUCKING LOVE L ARGININE AND DO NOT TAKE PROTEIN AND ISOLATED AMINO ACIDS WITHIN 45 MINS OF TAKING ONE OR THE ISOLATED AMINO WILL NOT WORK

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