Search results “Flagyl for c difficule”
Clostridium Difficile
A basic definition of Clostridium Difficile for Nurses C –diff is a bacteria that causes inflammation of the colon which is called colitis. Toxins produced by c-diff attack the intestinal lining. Those at high risk for C-diff are: • Elderly patients usually over the age of 65. • Those patients with recent hospitalizations • Patients with recent antibiotic C-diff usually occurs as a 3-step process: 1. First step is destruction of the normal flora (the current antibiotic may have killed good bacteria along with bad bacteria) 2. Ingests C-Diff bacteria (primarily acquired nosocomially as the spores can be abundant in the hospital environment) 3. Developments of C-diff disease – Usually around 7 day incubation. Signs and symptoms: • Abdominal cramping and pain • Watery stool ( 10-15 per day) • Dehydration • Fever • Renal failure • Pus or blood in stool Tests: • Stool cultures (can take several days to grow) • Colonoscopy/sigmoidoscopy Treatments: • Try to stop current antibiotic that triggered the illness if possible • Start new antibiotic to combat C-Diff bacteria (usually flagyl or vanco) • Surgery to remove part of colon affected • Probiotics – helps restore healthy organisms such as bacteria and yeast to help restore the healthy balance of the intestine. May also deter further C.diff infections. This bacteria can live on surface for a long period of time. It is found in feces. People become infected when they touch contaminated surfaces (hands, phones, tables, etc.) then touch their mouth. Prevention: Hand washing Contact precautions Clean equipment and room with chlorine bleach (bleach kills the spores) Learn more about this and other nursing topics at www.Nursestudy.net Facebook: http://www.facebook.com/NurseStudyNet
Views: 22951 NurseStudy Net
Clostridium Difficile
Update: Antibiotics for treatment of mild or moderate CDI include oral vancomycin or oral fidaxomicin; metronidazole has been an alternative agent. Oral vancomycin is suggested for the initial treatment of mild or moderate CDI; fidaxomicin has been associated with a lower recurrence rate but is substantially more expensive than vancomycin Use of metronidazole has been associated with treatment failure; the reasons are poorly understood. One contributing factor may be that stool drug levels in patients taking oral metronidazole decrease as colonic inflammation subsides, where stool drug levels in patients taking oral vancomycin or fidaxomicin remain high throughout the course of therapy.
Views: 50716 CanadaQBank
IBD School 222 C Difficile Therapy: Vanco, Flagyl, FMT
Muza-Moons discusses therapies for Clostridium difficile infection with antibiotics and stool transplant in #IBD patients.
Views: 44 Peter Higgins
Metronidazole vs Vancomycin in Mild Clostridium Difficile Infections
Lawrence J. Brandt, MD; Erik Dubberke, MD; Daniel E. Freedberg, MD, MS; Dale N. Gerding, MD; Yoav Golan, MD, MS; and Peter L. Salgo, MD, discuss provider considerations when making decisions on how to treat patients with Clostridium difficile with the guideline-suggested agents, vancomycin and metronidazole.
Views: 725 MD Magazine
Metronidazole Equaled Vancomycin for C. diff Diarrhea
Oral metronidazole was equivalent to oral vancomycin for the treatment of Clostridium difficile diarrhea, regardless of illness severity, investigators report.
Views: 4860 MDedge
My C Diff Experience with antibiotics !!!!
This my own on going personal expierance with C Diff from taking antibiotics for a bladder infection I had i started rotting symptoms on the 5th day of antibiotics and started getting worse on the last day I started puking out water and going 30 + times in a 24 hour period I knew something was wrong so I went to the Emergancy in pretty bad shape with extreme abdominal pain and diarrhea I suggest if you start having these symptoms that you rush to the hospital right away because you get sick and worse real fast!
Views: 3575 Maria's Vlogs
How I Beat C-Diff Without Antibiotics
Learn how you can fight C-Diff without antibiotics. Here is the study that gave me hope that turmeric would help eradicate the c-diff. http://farahmd.blogspot.com/2011/11/turmeric-enema-may-equal-vancomycin-for.html?m=1 http://healyourselfathome.com/HEALTH_PROBLEMS/INFECTIONS/C_DIFFICILE/C_DIFFICILE_TREATMENT/C_DIFFICILE_natural_pathogen_killers.aspx I also used this article to figure out how to actually do the turmeric enemas. I modified the protocol a little bit and only used the iodine enemas and the turmeric enema. I also purchased an enema bucket. See link below. http://www.drclark.net/disease-a-protocols/cancer-page/enemas This is what I ate while fighting C-diff: http://ohdeardrea.blogspot.com/2015/07/what-i-eat-my-new-c-diff-recovery-diet.html?m=1 The enema bucket I used to do the iodine/turmeric enemas: https://www.amazon.com/Kendall-Seamless-Enema-Bucket-145546/dp/B004FD7WRW/ref=sr_1_1?ie=UTF8&qid=1468187382&sr=8-1&keywords=enema+bucket Turmeric Tea recipe: https://draxe.com/recipe/turmeric-tea-recipe/ I substituted the ghee with coconut oil and the honey with liquid stevia. Where to buy Sacchromyces Boulardii: https://www.amazon.com/Jarrow-Formulas-Saccharomyces-Boulardii-Vegetarian/dp/B005P0K5LY/ref=pd_lpo_121_tr_t_2?ie=UTF8&psc=1&refRID=MTPZ6Z1M00YHZ9XX71XY
VANCOMYCIN - What You Need to Know
VANCOMYCIN - What You Need to Know Vancomycin is a bactericidal glycoprotein that binds to the d-Ala-d-Ala terminal of the nascent peptidoglycan pentapeptide side chain and inhibits transglycosylation. Vancomycin is indicated for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci. It is indicated for penicillin-allergic patients, for patients who cannot receive or who have failed to respond to other drugs, including the penicillins or cephalosporins, and for infections caused by vancomycin-susceptible organisms that are resistant to other antimicrobial drugs. Vancomycin is indicated for initial therapy when methicillin-resistant staphylococci are suspected, but after susceptibility data are available, therapy should be adjusted accordingly. Vancomycin is effective in the treatment of staphylococcal endocarditis. Its effectiveness has been documented in other infections due to staphylococci, including septicemia, bone infections, lower respiratory tract infections, skin and skin structure infections. When staphylococcal infections are localized and purulent, antibiotics are used as adjuncts to appropriate surgical measures. Vancomycin has been reported to be effective alone or in combination with an aminoglycoside for endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin has been reported to be effective only in combination with an aminoglycoside. Vancomycin has been reported to be effective for the treatment of diphtheroid endocarditis. Vancomycin has been used successfully in combination with either rifampin, an aminoglycoside, or both in early-onset prosthetic valve endocarditis caused by S. epidermidis or diphtheroids. Specimens for bacteriologic cultures should be obtained in order to isolate and identify causative organisms and to determine their susceptibilities to vancomycin. To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin and other antibacterial drugs, vancomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. VANCOMYCIN Mechanism of Action Vancomycin is an antibiotic drug which is structurally classified as a glycopeptide. It mainly acts by prevention of cell-wall biosynthesis of bacteria. It is specially effective against gram-positive bacteria and has been known to be effective against resistant strains of MRSA. Vancomycin is known as the drug of last resort as it generally used when all other treatments have failed. However, bacteria have started developing resistance to vancomycin as well- leading to use of other antibiotics. Vancomycin acts by inhibiting cell wall synthesis of bacteria. Peptidoglycan layer of the cell wall is rigid due to its highly cross-linked structure. During the synthesis of the peptidoglycan layer of bacteria, new building blocks of peptidoglycan get inserted (i.e. monomers of N-acetylmuramic acid and N-acetylglucosamine) into the membrane.Vancomycin inhibit the synthesis of bacterial cell wall phospholipids as well as peptidoglycan polymerization in a time dependent fashion by binding to the D-ala-D-ala side chain of the precursor pentapeptide.This prevent the transglycosylation step in peptidoglycan polymerization . By doing so, vancomycin makes the peptidoglycan layer less rigid and more permeable. This causes cellular contents of the bacteria to leak out and eventually death of the bacteria. Mutations in the transpeptidase enzyme can lead to increased resistance to vancomycin. Adverse Effects more than 10% Bitter taste (PO) Erythematous rash on face and upper body (IV; red neck or red man syndrome; related to infusion rate) Hypotension accompanied by flushing (IV) Nausea and vomiting (PO) 1-10% Chills (IV) Drug fever (IV) Eosinophilia (IV) Rash (IV) Fatique (PO) Peripheral edema (PO) Urinary tract infection (PO) Back pain (PO) Headache (PO) Reversible neutropenia (IV) Phlebitis (IV) less than 1% Nephrotoxicity Ototoxicity (especially with large doses) Stevens-Johnson syndrome Thrombocytopenia Vasculitis
Views: 9166 Medinaz
Antibiotic Treatment with Metronidazole / Flagyl
Treatment with metronidazole (Flagyl) is common, and the basics of this antibiotic therapy are reviewed by Dr. Greg Hall.
Views: 81377 Dr. Greg Hall
Vancomycin: What You Need to Know
Quick overview of vancomycin! Check us out on Facebook for DAILY FREE REVIEW QUESTIONS and updates! (https://www.facebook.com/medschoolmadeeasy) Check out our website for TONS OF FREE REVIEW QUESTIONS! (http://medschoolmadeeasy.com/) Thanks for stopping by, and we love hearing from you! Disclaimer: the information in this video only represents the knowledge and property of the video’s authors- no one else.
Views: 30873 Med School Made Easy
C. Difficile – What it is, Symptoms, Recurrence, Mortality, Costs and Prevention
C. Difficile – What it is, Symptoms, Recurrence, Mortality, Costs and Prevention Clostridium difficile, or C. difficile as it’s commonly known, is a bacteria that causes diarrhea and, in some cases, serious conditions such as colitis, bowel perforations, sepsis and even death. It is one of the most common infections found in hospitals and long-term care facilities and the most frequent cause of infectious diarrhea. The people most at risk of contracting C. difficile include: people in health-care settings, the elderly, people taking antibiotics, chemotherapy and immunosuppressed patients, people with a severe underlying illness and people with gastric acid suppression. C. difficile is highly contagious and can spread from person-to-person or within healthcare settings. The spores can survive for months on surfaces touched by hands such as: Floors, toilets, linens and more. To learn more and consult the references, please watch the video!
Metronidazole or Flagyl Medication Information (dosing, side effects, patient counseling)
Your Medication Metronidazole Metronidazole is also known by the brand name: Flagyl. Metronidazole comes in 250, and 500 mg tablets, 375 mg capsule, 750 mg tablet, and 50 mg/mL and 100 mg/mL oral liquid. Metronidazole is most commonly used for abdominal and gynecological infections. No matter what your doctor has you taking it for, metronidazole is usually taken by mouth 2 to 3 times a day. Some types of metronidazole need to be taken on an empty stomach, while others can be taken with food. If you miss a dose, take the missed dose as soon as you think about it. If it is close to time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not take 2 doses at the same time or extra doses. Some common side effects with metronidazole include headache, upset stomach, and yeast infections. Some less common side effects include dizziness and a metallic taste in your mouth. Do not take metronidazole and drink or use alcohol. While taking metronidazole, remember it is important to tell your doctor or pharmacist if: • You are being treated for alcohol dependency • You are pregnant or may become pregnant All forms of metronidazole including the liquid needs to be stored at room temperature in a dry place. Use the measuring device received from the pharmacist or doctor for the oral liquid.
Views: 665 UAMS COPmedia
Recurrent C. diff infections
Researchers from the Perelman School of Medicine at the University of Pennsylvania have found evidence that the most difficult C. difficile cases, known as multiple recurring C. difficile infections (mrCDI), are rapidly becoming more common. This is documented in a recent study published in the journal, Annals of Internal Medicine. Lead author and Professor of Medicine in the Gastroenterology Division and Senior Scholar in the Center for Clinical Epidemiology and Biostatistics at the Perelman School of Medicine at the University of Pennsylvania, James Lewis, MD joined me to discuss the study, the findings and the use of fecal microbiota transplantation (FMT). Outbreak News Today http://outbreaknewstoday.com/ Outbreak News Interviews on iTunes https://itunes.apple.com/us/podcast/outbreak-news-interviews/id1249586204?mt=2&ls=1
Views: 76 Outbreak News TV
Seeing Advancement in the Treatment of C-Diff
Whether it is medication or fecal microbiota transplantation work in the field of treating clostridium difficile is making great strides every day.
Views: 255 MD Magazine
Medical School - Clostridium Difficile Infection
Follow us on Twitter: https://twitter.com/iMedSchool Follow us on Facebook: https://www.facebook.com/Imedicalschool?ref=hl iTunes Podcast: https://itunes.apple.com/us/podcast/imedicalschool/id577103998?mt=2 Website: www.medpulse.org Discussion of the types of c. diff, pathogenesis, diagnosis and treatment of c. diff colitis. iMedicalSchool is a channel dedicated to helping you understand complex medical topics in a simple manner. We are dedicated to making sure that you understand every topic presented. We are happy to answer questions and take suggestions. No matter if you are in medical school, nursing school or physician assistant school we are here to serve you.
Views: 25647 iMedicalSchool
Clostridium difficile (c.diff) Infection | Gastrointestinal Society
Bacterial infection with C. difficile inflames the colon and causes diarrhea – that can be debilitating – and other intestinal symptoms. Infection with Clostridium difficile is very serious, can often recur, and can even lead to death. Franҫais: https://youtu.be/26d8COMHZQw The Gastrointestinal Society, a registered Canadian charity, provides trusted, evidence-based information on all areas of the gastrointestinal tract, and is committed to improving the lives of people with GI and liver conditions, supporting research, advocating for appropriate patient access to health care, and promoting gastrointestinal and liver health. For more free information on this and other information on digestive diseases and disorders, please visit our website http://www.badgut.org/ The information contained in this video is in no way intended to replace the knowledge or diagnosis of your health care provider. We advise seeking a physician or medical professional whenever a health problem arises requiring an expert's care. © 2016. Gastrointestinal Society.
How to Treat C. Difficile Infection Naturally - VitaLife Show Episode 257
Treating C. Difficile Infection Naturally - VitaLife Show Episode 257 In today's episode Dr. Janine Bowring shares with us how to treat C Difficile naturally. C Difficile is a common bad bacterial infection that is localized to the gut. This bacterial infection is usually picked up through a hospital setting. Avoid having to go to the hospital if you can, especially as a patient but even when visiting (hopefully your loved ones are healthy around you). It can be treated naturally, but you need to be forceful and do things in the right way. Prevention is key, because you want to prevent any bad bacteria adhering to your system and digestive tract. By maintaining good levels of probiotics, your healthy good gut flora in your digestive tract, your immune system will be strong and ready to fight any bad bacteria. Probiotics are to be taken on a daily basis not only to prevent but also to maintain a healthy immune system. Apple Cider Vinegar naturally occurring is a great way to make sure you have enough stomach acidity to fight off that bad bacterium, if you come in contact with them. Apple Cider Vinegar 1 tablespoon a day, in a large glass of water helps to regulate your digestive tract and helps to maintain your good gut flora. It is also very important to maintain a healthy diet, whole foods such as vegetables, fruit, nuts, seeds, whole grains and legumes. Drink plenty of water to hydrate your body and flush out toxins. To keep your body strong, healthy and fit but also to keep your digestive tract in that top condition. Processed foods and sugars feed bacteria, the less sugar in your diet the less the bad bacteria has to feed off of. Go to our website for more information www.vitatree.com. Join us next time for more great videos! VitaTree Website: https://www.vitatree.com Like us on Facebook: https://www.facebook.com/vitatree Follow us on Twitter! https://twitter.com/VitaTree Follow us on Instagram: www.instagram.com/VitaTree Follow us on Pinterest: www.pinterest.com/vitatree These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose,treat,cure or prevent any disease. https://youtu.be/7oFTQCfJcpU -~-~~-~~~-~~-~- Please watch: "How To Do An Easy Full Body Detox - VitaLife Show Episode 265" https://www.youtube.com/watch?v=hPIECMYNHoA -~-~~-~~~-~~-~-
Clostridium Difficile Infection (Pseudomembranous Colitis)
Thanks for watching! Please like, comment subscribe and share :) To download this presentation click here: https://www.dropbox.com/s/63lkroclhygdjtg/Pseudomembranous%20Colitis.pptx?dl=0 Please check out our Patreon page here: https://www.patreon.com/howtogastro You can like our facebook page here: https://www.facebook.com/howtogastro You can follow us on instagram here: https://www.instagram.com/howtogastro
Views: 1254 How To Gastro
Treating C. difficile: The Downside to Current Approaches
Stuart Johnson, MD, infectious disease clinician in the Medicine/ID department at Loyola University Medical Center, discusses the disadvantages to some of the current approaches used to treat C. difficile.
Views: 78 Contagion_Live
C Diff Symptoms -- 6 Early Signs you Shouldn't Ignore!
http://utahtexans.com/ Click on the link above for a free video guide to shopping for dietary supplements. I'm going to share with you the major C diff symptoms, how someone gets this health problem as well as some interesting ideas on treating it. As you can probably tell C diff is short for something, and that is clostridium difficile. Sounds like a magic spell. In a nutshell it's a bacterial infection in the digestive system that causes all kinds of problems. Unfortunately every year this bacteria gets more people sick and kills more people. These bacteria create little spores that are survival machines almost like roaches. The spores of C diff can survive for years traveling in the air and on surfaces, and They can be inhaled or ingested accidentally. This is why many people actually have these bacteria in their system right now. The reason not everyone gets sick is because good bacteria are keeping them in check. Here comes antiobiotics, which are supposed to be helpful and do help with certain things but they kill off the good bacteria. The C Diff bacteria can they grow unchecked and bring about as much harm as an unruly mob. One of the most common symptoms of C diff is watery diarrhea a few times a day. Interestingly enough if you just look at your stools it can tell you a lot about your health. Stools should gently slide in the toilet making a tiny splash like an Olympic diver. Stools that are white, yellow, grey or bloody are all bad signs. Lastly floaters, ones that splash majorly, watery stools and of course ones that are painful are all bad signs. I bet you never thought you would be learning about stools today right? Another very common sign of a C diff infection is abdominal pain. Some other signals could be a fever, loss of an appetite, blood or pus in stools, nausea and someone losing weight abnormally. The very sad thing with this disease is that many people might brush these symptoms off as being normal or nothing serious. This isn't the right move because in some cases C diff can bring about damage in the digestive tract that can be fatal. Besides putting holes in your digestive tubes C diff can lead to kidney failure, which can also be fatal. I understand doctors can be expensive and sometimes it's not worth it to see one. My thoughts on when to see a doctor are determined by your inner voice, which is usually very wise. Unless you're around beautiful women then sometimes it gets stupid, at least sometimes mine does. If you think for a second something is seriously wrong then it's best to see a doctor right away, and not second guess yourself. The best thing someone can do to avoid C diff is to wash their hands. Sounds silly and common sense, but sometimes the most effective things are the simplest right? Antibiotics, which should only be taken if you absolutely have to. Try to chew your food a lot before you eat it, this helps release digestible enzymes. The next thing you can do is take prebiotics. No this stuff is not in yogurt, that is called probiotics and there is a big difference. Prebiotics are found in nature while probiotics are man-made and are usually found in yogurt. Companies that sale yogurt want you to believe that probiotics are the greatest thing since sliced bread. They do add some good bacteria, but they can be killed easily, and don't do a lot to help. Prebiotics help good bacteria by enabling them to reproduce a lot, and this is way more helpful. The easiest way to get prebiotics would be by taking a dietary supplement, or you can get it by eating 1,000 kiwis a day. Ok, maybe the stuff in supplements isn't 1,000 kiwis, but it's a lot. Before you go out and buy a bunch of prebiotic supplements, I want to warn you of something. There are a lot of crappy dietary supplements on the marketplace. The reason for this is because in many countries the laws that regulate the industry are about as loose as MC Hammer's pants To make things easier for you I've created a free video guide on shopping for dietary supplements. It talks about how to identify a good product from a risky one, and much more like herbal remedies and what to take for certain conditions. I think you're really going to like it and you don't have much to lose by checking it out, since it's free. You can view this guide at http://texasvitamins.com/go/youtube.html.
Views: 62664 kwhitsitt1
What is C. diff and why should I care?
Have you heard of Clostridium difficile, or C. diff? Watch and learn about this potentially deadly infection.
Views: 1081 Prepper Potpourri
Clostridium dificile
Clostridium Notes: https://drive.google.com/open?id=0B1opKPCEPfC_Vm1Xb0RpeUhsR1UwNHpWMUlNUy1lUXQzaFhz
Views: 4119 susannaheinze
Clostridium Difficile Infection & Pseudomembranous Colitis
Subscribe to this channel: https://www.youtube.com/channel/UCKDwY2bhQtcMUZ3UFdN3Mng?sub_confirmation=1 Other Infectious Disease Lectures: https://www.youtube.com/playlist?list=PLfBFwAwues0nUpkmeLncvvUV315dXVo4o Clostridium difficile infection (CDI or C-dif) is a symptomatic infection due to the spore-forming bacterium, Clostridium difficile. Symptoms include watery diarrhea, fever, nausea, and abdominal pain. It makes up about 20% of cases of antibiotic-associated diarrhea. Complications may include pseudomembranous colitis, toxic megacolon, perforation of the colon, and sepsis. Clostridium difficile infection is spread by bacterial spores found within feces. Surfaces may become contaminated with the spores with further spread occurring via the hands of healthcare workers. Risk factors for infection include antibiotic or proton pump inhibitors use, hospitalization, other health problems, and older age. Diagnosis is by stool culture or testing for the bacteria's DNA or toxins. If a person tests positive but has no symptoms, the condition is known as C. difficile colonization rather than an infection. Prevention is by hand washing, terminal room cleaning in hospital, and limiting antibiotic use. Discontinuation of antibiotics may result in resolution of symptoms within three days in about 20% of those infected. Often the antibiotics metronidazole, vancomycin or fidaxomicin will cure the infection. Retesting after treatment, as long as the symptoms have resolved, is not recommended, as the person may remain colonized. Recurrences have been reported in up to 25% of people. Some tentative evidence indicates fecal microbiota transplantation and probiotics may decrease the risk of recurrence. Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the stool resembling horse manure. In a population of hospitalized patients, prior antibiotic treatment plus diarrhea or abdominal pain had a sensitivity of 86% and a specificity of 45%. In this study with a prevalence of positive cytotoxin assays of 14%, the positive predictive value was 18% and the negative predictive value was 94%. In children, the most prevalent symptom of a CDI is watery diarrhea with at least three bowel movements a day for two or more days, which may be accompanied by fever, loss of appetite, nausea, and/or abdominal pain. Those with a severe infection also may develop serious inflammation of the colon and have little or no diarrhea. Metronidazole typically is the initial drug of choice for mild to moderate disease, because of lower price. Typically, it is taken three times a day for 10 days. Vancomycin by mouth is preferred for severe disease. Additionally, vancomycin may be used to treat mild-to-moderate disease if diarrhea persists after a course of metronidazole. Since metronidazole has the potential to cause birth defects, pregnant women with Clostridium difficile infection may be treated with vancomycin regardless of disease severity. Vancomycin may be more effective than metronidazole. Typical vancomycin dosage is taken four times daily for 10 days. It may be given rectally if the person develops an ileus and cannot take medications by mouth. Fidaxomicin has been found to be as effective as vancomycin in those with mild to moderate disease, and may be better in those with severe disease. It is tolerated as well as vancomycin, and may have a lower risk of recurrence. It may be used in those who have recurrent infections and have not responded to other antibiotics. Medications used to slow or stop diarrhea, such as loperamide, may worsen C. difficile disease, so are not recommended. Cholestyramine, an ion exchange resin, is effective in binding both toxin A and B, slowing bowel motility, and helping prevent dehydration. Cholestyramine is recommended with vancomycin. A last-resort treatment in those who are immunosuppressed is intravenous immunoglobulin. https://en.wikipedia.org/wiki/Clostridium_difficile_infection
Clostridium difficile Update
A Division of Hospital Medicine Grand Rounds presented by Timothy Sullivan, MD, Assistant Professor of Medicine (Infectious Diseases).
Clostridium difficile  Emerging Issues and Treatments
Clostridium difficile infection is an important cause of intestinal disease, primarily affecting hospitalized patients exposed to antibiotics. Infection has been associated with prolonged hospital stays and excess healthcare expenditures.Recent changes in epidemiology of this disease show a rise in community-acquired cases in people outside the hospital settings without traditional risk factors.Participants will discuss this disturbing trend as well as the potential role of animals and the food supply and the status of current vaccine development efforts. Erik Dubberke, MD, Washington University School of Medicine, St. Louis, MO Glenn Songer, PhD, Iowa State University, Ames, IA Clifford McDonald, MD, Centers for Disease Control and Prevention, Atlanta, GA
Q&A with Colleen Kelly: Treatment Options for C. Difficile Infections
Colleen Kelly, MD, FACG, Brown University shared at the 2015 American College of Gastroenterology Annual Scientific Meeting that they're seeing more C. Diff infections in even populations of people that were previously thought to be at low risk. As such, Kelly and colleagues work to stratify it by how severe the infection is and what antibiotics to use to treat mild/moderate to more severe infections.
Views: 769 MD Magazine
In C. difficile, Are Two Drugs Better Than One?
Combining metronidazole and vancomycin was not more effective than either drug alone for treating C. difficile infection in a retrospective study of 248 patients, explains Dr. Jessica C. Njoku.
Views: 612 MDedge
C. difficile: Different Symptoms, Different Strains
Sebastien Lefebvre teaches us about C. difficile in a way that makes it si facile to understand. This video was produced and edited by Science Communication student Erica Richard. Eagle Awards Winner for best director, Erica Richard. Music: Perspectives by Kevin Macleod @ http://incompetech.com/
Views: 2564 Science Communication
Fidaxomicin in the Treatment of Clostridium Difficile Infections
Erik Dubberke, MD; Yoav Golan, MD, MS; and Peter L. Salgo, MD, compare the use of fidaxomicin against standard therapy options, such as vancomycin, for the treatment of Clostridium difficile, suggesting that fidaxomicin may reduce a patient’s risk of recurrence.
Views: 588 MD Magazine
How Antibiotics Cause Infections (C. Diff)
Gastroenterologist Dr. Scott Wilhoite explains how antibiotics can wipe out the good bacteria in the colon, allowing a bad bacteria called clostridium difficile (C. diff) to spread and cause a potentially fatal infection. Diagnosis and treatment of C. diff are also explained. Watch hundreds of other health videos at http://www.youtube.com/user/DrBobShow1.
Views: 1635 The Dr. Bob Show
Clostridium difficile (c diff) living in a c diff paradise
What is Cdiff? Cdiff is an infection of the colon that is acquired most often with antibiotic use. The human gut flora is altered and not as effective after multiple doses of antibiotics. Cdiff bacteria is passed in feces and spread to and objects (stethscopes, door handles etc when people don’t wash their hands). You might unknowingly swallow the bacteria Your intestines contains millions of bacteria, many of which help protect your body from infection but when you take an antibiotic to treat an infection the drug can destroy normal bacteria. Cdiff can produce toxins that attack the lining of the intestines. The toxins can destroy cells and produce patches of inflammatory cells that cause watery diarrhea. Symptoms? Diarreha! Is the most common and range from soft and unformed to watery or mucoid in consistency with . Patients can have 20 bowel movements a day. Fever abdominal pain, elevated leukocytosis Treatment- hydration Flagyl and vancomycin IV Vancomycin is ineffective for the treatment of cdiff For sever cdiff that keeps recurring or isn’t improving with antibiotics Sigmoidoscopy and Colonscopy CT of abdomen. Surgical colectomy may be life saving if there is no response to medical management Fecal transplant- restores healthy intestinal bacteria by placing another persons stool in your colon, using a ngt or colonscope. The success rate is high for treating patients with cdiff clostridium difficile c diff clostridium difficile colilits
Views: 399 Danielle Hardin
(CC) Vancomycin, MRSA, and Clostridium Difficile, (CH 4 IMMUNE NAPLEX / NCLEX PHARMACOLOGY REVIEW)
Free Pharmacology Resources: https://www.memorizingpharmacology.com/ Audiobook: https://www.amazon.com/Memorizing-Pha... Video series to support the book Memorizing Pharmacology. I go through some practice and very memorizable NAPLEX, NCLEX pharmacology review style questions.
Views: 990 Tony PharmD
Beaumont researching way to stop C. difficile infections
Beaumont researchers believe a drug called vancomycin, which is normally used to treat C. diff infections, can also keep the C. diff in check. If successful, this research could potentially save thousands of lives, stop tens of thousands of infections and save millions of health care dollars.
Views: 403 Beaumont Health
When to Suspect Diarrhea is Symptom of a Clostridium Difficile Infection
Lawrence J. Brandt, MD; Erik Dubberke, MD; Dale N. Gerding, MD; Yoav Golan, MD, MS; and Peter L. Salgo, MD, distinguish between small bowel and large bowel diarrhea in patients with Clostridium difficile and discuss common approaches for diagnosing and managing patients.
Views: 884 MD Magazine
Treatment and Prevention of Clostridium difficile Infection
Robin L. P. Jump, MD, PhD, Geriatric Research, Education and Clinical Center (GRECC), Louis Stokes Cleveland VA Medical Center; Assistant Professor of Medicine, Division of Infectious Diseases and HIV Medicine, Case Western Reserve University, Cleveland This session will address the risk factors for developing C. difficile infection, discuss treatment options for C. difficile infection, including recurrent disease and describe infection control interventions to reduce the risk of C. difficile transmission.
Fecal Transplantation to Treat C. Difficile Infections
Fecal transplantation through colonoscopy is an effective treatment for recurrent C. difficile infections according to a Finnish study published in the journal, Gastroenterology. Fresh homogenized donor stool was implanted into the cecum. Results were nearly 100% effective compared to the standard treatment with Vancomycin and Cholestyramine. Symptoms disappeared over 12 weeks and no side effects were seen over a one year follow up period. While this is very effective treatment, so is the use of a nutritional protocol that uses probiotics, l-glutamine, and a number of nutrients such as what is found in many products such as UltraClear Sustain, and implantation is unnecessary. Nonetheless, this is a very good backup approach that can be highly effective. For more information please visit www.doctorsaputo.com
Views: 2895 DoctorSaputo
Fecal Transplants to Treat C. Diff Explained by Drexel Medicine Gastroenterologist
Drexel gastroenterologist Neilanjan Nandi, MD, specializes in treating people with difficult cases of C. difficile who haven't responded to standard medical treatments. As Nandi explains, one therapy that has shown to be highly effective is a fecal transplant.
Views: 568 Drexel Medicine
Next Generation Probiotics Targeting C  Difficile Infection
Presented at Microbiology & Immunology 2017 https://www.labroots.com/virtual-event/microbiology-2017 Jennifer Spinler, PhD, Instructor, Pathology & Immunology, Baylor College of Medicine Dr. Spinler is an experienced classical microbiologist with extensive training in bacterial genetics and genomics currently serving as faculty at Baylor College of Medicine in the Texas Children's Microbiome Center. Her expertise in developing mutagenesis systems for investigations of gram-positive bacteria which has contributed to recent successes with genetics of probiotics; particularly in the area of antimicrobial production by Lactobacillus reuteri. Current research efforts combine comparative and functional genomics strategies with animal models and microbiome research to understand how individual probiotic organisms beneficially impact the larger microbiome community of the gastrointestinal tract and how these interactions protect against antibiotic-associated disease. Specifically, her research is aimed at developing adjunct probiotic therapies targeting C. difficile infection. As a probiotic researcher in a hospital-based microbiome center, Dr. Spinler has the benefit of combining her expertise with clinically relevant microbiome studies which has tremendous potential to impact our basic understanding of mechanisms of bacterial resistance and create new translational opportunities combatting antimicrobial resistance. Next Generation Probiotics Targeting C Difficile Infection Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to C. difficile antibiotics (vancomycin, metronidazole and fidaxomicin), we determined that L. reuteri strains are ideal adjunct therapy candidates. We evaluated the ability of reuterin - a secondary metabolite produced by specific strains of L. reuteri during fermentation of the prodrug glycerol - to inhibit C. difficile growth in vitro. We found that levels of reuterin produced by L. reuteri 17938 were more potent than vancomycin in inhibiting C. difficile growth. Using human fecal microbiota bioreactors, we showed that co-delivery of L. reuteri with glycerol is effective against C. difficile colonization of a complex-microbial community, whereas treatment with either glycerol or L. reuteri alone was ineffective. Co-delivery of L. reuteri and glycerol changed microbial community profiles and associated metabolites consistent with glycerol fermentation and reuterin production. Ex vivo studies showed that this combination therapy resulted in lower C. difficile burden and toxicity in stool and that this was dependent upon reuterin production. Taken together, prodrug-based adjunct therapy with probiotic L. reuteri is a viable option for preventative treatment of C. difficile infection. Earn PACE/CME Credits: 1. Make sure you’re a registered member of LabRoots https://www.labroots.com/virtual-event/microbiology-2017 2. Watch the webinar on YouTube or on the LabRoots Website https://www.labroots.com/virtual-event/microbiology-2017 3. Click Here to get your PACE (expired 9/14/2019) –https://www.labroots.com/credit/pace-credits/2464/confirm LabRoots on Social: Facebook: https://www.facebook.com/LabRootsInc Twitter: https://twitter.com/LabRoots LinkedIn: https://www.linkedin.com/company/labroots Instagram: https://www.instagram.com/labrootsinc Pinterest: https://www.pinterest.com/labroots/ SnapChat: labroots_inc
Views: 152 LabRoots
Mayo Clinic Study Reports Increasing Incidence of C. difficile Infection
A study presented by Mayo Clinic provides clear evidence that the number of people contracting the hard-to-control and treat bacterial infection Clostridium difficile (C. difficile or C. diff) is increasing, and that the infection is commonly contracted outside of the hospital. Results of the study showed that the incidence of C.difficile infection (CDI) in children was more than 12 times higher between 2004 and 2009, compared to the period 1991--1997 (32.6 cases per 100,000 vs. 2.6). In addition, 75 percent of cases were "community-acquired," meaning that the patients had not been hospitalized for at least four weeks prior to contracting C. difficile. Dr. Sahil Khanna, the lead author or the study, discusses the research.
Views: 5999 Mayo Clinic
C Diff Nurse-Driven Testing Protocol
A review of c-diff infections.
Views: 805 Janis Provinse
Clostridium difficile   quick review
Fmgsindia.com provides free, useful resources for medical students preparing for postgraduate entrance Examinations. Check our website for more information.Short, comprehensive video lectures designed to integrate knowledge of the basic sciences to clinical applications and context. ENGAGE Subscribe to our channel: http://www.youtube.com/user/fmgsindia?sub_confirmation=1 Leave a comment, thumbs up the video (please!) * learn more : http://www.fmgsindia.com/ Connect us for more information Twitter: https://twitter.com/fmgsindia Facebook: https://www.facebook.com/Fmgsindiaofficial/ Google+:https://plus.google.com/+fmgsindiacrackfmge Website: http://www.fmgsindia.com/ -~-~~-~~~-~~-~- Please watch: "Bevacizumab quick review -anticancer drugs-pharmacology" → https://www.youtube.com/watch?v=-JICcTfJ7hU -~-~~-~~~-~~-~-
Views: 1803 Rewise MD
Failure to detect C. difficile is failure to prevent deadly infections.
Don’t ignore the facts. Rapid and accurate detection of toxigenic C. difficile with Xpert® C. difficile/Epi can help stop the spread of deadly infections. A quick check of the facts: • Over 29,000 patients in the US die each year from C. difficile infections (1) • Toxin testing fails to detect some patients with symptomatic and even life-threatening C. difficile infections (2-4) • Patients colonized with toxigenic C. difficile can spread infection to others and are at increased risk of developing symptomatic infections (5,6) References: 1.) Lessa FC, et al. N Engl J Med. 2015;372:2369-70. 2.) Cohen SH, et al. Infect Control Hosp Epidemiol. 2010;31:431-55. 3.) Surawicz CM, et al. Am J Gastroenterol. 2013;108:478-98. 4.) Dallal RM, et al. Ann Surg. 2002;235:363-72. 5.) Curry SR, et al. Clin Infect Dis. 2013;57:1094-102. 6.) Tschudin-Sutter S, et al. Infect Control Hosp Epidemiol. 2015;36:1324-9 For in vitro diagnostic use. Test may not be available in all countries. Cepheid 904 Caribbean Drive Sunnyvale , CA 94089 +1-408-541-4191 United States website: http://www.cepheid.com/
Views: 997 CepheidNews
Why Do Some Patients Experience Recurrence of Clostridium difficile Infections After Treatment?
Julian Hurdle, PhD, Associate Professor, Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center explains why some patients experience recurrence of Clostridium difficile after treatment.
Views: 141 Contagion_Live
Treatment Options for Newly Diagnosed C. Difficile
Dale N. Gerding, MD; Yoav Golan, MD; Darrell S. Pardi, MD; and Peter Salgo, MD, highlight treatment options, such as vancomycin and fidaxomicin, used in the management of Clostridium difficile infection and consider the risk for recurrence.
Views: 34 MD Magazine
Natural Health Reviews - C. Difficile
Introducing National Nutrition's newest Youtube series "Natural Health Reviews". We sit down with Naturopathic Doctor Jonathan Beatty, as he tells us about C. Difficile and what this hospital acquired illness is. To read more about C. Difficile please click here: http://www.nationalnutrition.ca/HEALTHCONCERNS_C_DIFFICILE.aspx Despite the name, C. Difficile, the most common nosocomial infections (meaning hospital acquired) in North America, may actually be much less difficult to treat than we think. Antibiotics strip our gut of not only the 'bad bacteria', but the healthy, normal and essential gut flora, as well. This leaves opportunistic bacteria ('bad') with a breeding ground for infection, unopposed by our natural defences in the form of healthy bacteria.… To view more interviews with Health Care Professionals, click here: https://www.youtube.com/playlist?list=PLFydSZTC8qlbk7KPenG1bwPd8KDniLEbF Visit us at http://www.nationalnutrition.ca/
Views: 67 National Nutrition
Making a diagnosis of Clostridium difficile
Dr. John Bartlett describes the methods for diagnosing C.diff., when to suspect, and what are the best tests to confirm a diagnosis. For more information on infectious diseases, visit http://www.impactid.tv/
Views: 310 impactID.com
Lisa - C. diff survivor
C. diff survivor and Peggy Lillis Foundation Advocates Council member Lisa talks about her experience with the disease.
c diff diet