Home
Search results “Differene between verapamil and diltiazem” for the 2016
Confused about DILTIAZEM Formulations?
 
02:40
Learn different formulation about diltiazem hydrochloride
Views: 400 SomaliMedicine
Potassium channel blockers
 
13:13
Potassium Channel Blockers are easy! Check it out! I work hard to make and find the best videos for you to study from (it’s not easy)! You can help by suggesting any good videos you've seen in the comments below! Good luck in school!! Hey, guys. This is Dr. Joel with MedImmersion. You are watching a flash flood review series video where I review the highest yield stuff for your board exams in as little time as possible. In this video, I'm going to be talking about the potassium channel blockers, which are a class of the antiarrhythmic agents. I'll cover some general principles about the class as a whole, and then a few specific drugs in that category, or in this class. It's gonna be awesome, so stick around. If you watch a lot of MedImmersion videos, and they're helpful for you, think about getting an account at medimmersion.com. That will speed you up in your studying because when you're logged into MedImmersion on your browser and use the links in these videos, you will automatically skip past these lengthy introductions on my MedImmersion videos and also on other people's videos that I've linked to. And you'll be able to skip over a lot of the YouTube advertisements on my MedImmersion videos. Okay. Let's jump into it. This lecture is going to cover a subset of the antiarrhythmics, the potassium channel blockers. I'll give you an introduction as to what they are. Then, talk about some general principles that will include the mechanism of action, clinical uses, adverse or side effects, and then I will cover a couple of the highest yield examples in this class. Alright. First of all, if you need to review the entire topic of the antiarrhythmics, with a little bit of cardiac physiology, you should really go over and watch The Antiarrhythmic Agents Lecture first. This lecture, right now, is a little bit more focused, and I assume that you know a couple of things about antiarrhythmics. So, the potassium channel blockers, in the Vaughn Williams Antiarrhythmic Agent Classification, are the Class III antiarrhythmics. You should know that. And we use the potassium channel blockers and the Class I, or sodium channel blockers, for rhythm control. The Class IIs and Class IVs are more rate control. Four drugs that we're gonna talk about amiodarone, ibutilide, dofetilide, and sotalol, which you can remember by the mnemonic AIDS. As for the mechanism of action, these block myocardial potassium channels, and that has its primary effect on the specific potassium channels that are responsible for the delayed rectifier current, which have a very important contribution on the length of the action potential, and thus, the effective refractory period of cardiac myocytes. And to explain that a little bit further. Have you ever wondered why exactly the action potential of a neuron through the spinal cord or a peripheral neuron looks different than the action potential in myocardium. Well, it's built that way on purpose. The plateau phase, or the prolongation of the action potential, or the refractory period, gives cardiac tissue special properties that prevent it or contribute to prevention of arrhythmias. So, the picture on the left is what maybe a bland neuron action potential might look like in the peripheral nervous system. On the right, we have a cardiac action potential. And both of these are pretty bland images. They're not exactly right. But the point here is that there's a plateau where the cell stays in its non-polarized state for a little bit longer, for a period of time. Potassium plays a big part in that. The initial depolarization is caused by a rapid influx of sodium. And then, it's maintained in that depolarized state by both calcium and potassium trading places across the cell membrane in relatively small amounts. In phase three, which is the repolarization phase, finally there's a delayed switch, or a delayed rectifier current of potassium, which finally turns on and allows an efflux of positive ions, allowing the membrane potential to come back down to a very negative number. So, hopefully you can see why if we mess around with the potassium channels that contribute to phase three, we prolong or at least change the shape of the cardiac action potential, which, of course, would have an effect on some kinds of arrhythmias. So, it was pretty easy to see, I think, from that previous picture that delaying the potassium efflux during the repolarization phases increases or stretches out the action potential duration and also the effective refractory period. Also, these do not have any effect on the sodium channels, meaning that the conduction velocity, or phase zero, wouldn't be affected or decreased. And visually, it looks like this, the action potential stretched out and the effective refractory period is increased. Also, that means that the QT interval is prolonged. Okay. Does that make sense? We use the Class III antiarrhythmic agents for rhythm control.
Views: 7028 Med Immersion
If You’re On Any Of These Medications, DO NOT Use Apple Cider Vinegar
 
04:01
Although ACV is best known for its many health benefits, it is also very important to know that this amazing vinegar can cause side effects http://healthyfoodspot.com/2016/09/11/if-youre-on-any-of-these-medications-do-not-use-apple-cider-vinegar/
Views: 2130798 Article-TUBE2
Amlodipine Nursing Considerations, Side Effects and Mechanism of Action Pharmacology for Nurses
 
04:37
Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://www.nrsng.com/50meds View full post: https://www.nrsng.com/amlodipine-norvasc/ Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/ Amlodipine Generic Name: Amlodipine Trade Name: Norvasc Indication: hypertension, angina Action: blocks transport of calcium into muscle cells inhibiting excitation and contraction Therapeutic Class: antihypertensive Pharmacologic Class: Ca channel blocker Nursing Considerations  may cause gingival hyperplasia  grapefruit juice may increase drug level  monitor blood pressure and pulse prior to and during therapy  monitor intake and output  assess for signs of CHF  assess characteristics of angina  instruct patient of interventions for hypertension and how to take blood pressure
Views: 8896 NRSNG
(CC) Top 200 Drugs Chapter 6 Cardio Nursing Pharmacology by Suffix (Memorizing Pharmacology)
 
27:05
FREE Audiobook: https://www.amazon.com/Memorizing-Pharmacology-A-Relaxed-Approach/dp/B01FSR7XZO/ Allnurses.com article: http://allnurses.com/nursing-student-assistance/memorizing-pharmacology-video-1111129.html Website: https://www.memorizingpharmacology.com/ Top 200 Drugs Pronunciation and Mnemonics and review of prefixes, infixes, and suffixes of medications to go with book Memorizing Pharmacology: A Relaxed Approach / How to survive nursing school pharmacology
Views: 29702 Tony PharmD
USMLE Cardiovascular System 17 - Varicose Veins/Vasculitis/Raynaud's
 
09:59
Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and resultant damage. Although both occur in vasculitis, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities.
Bisabolol
 
04:50
12.Januar 2016 by Lavaskop
ESC 2015: Dual antiplatelet therapy in unstable angina - Prof Gislasen
 
03:05
Professor Gunnar Gislasen, Gentofte University Hospital, Denmark, talks to Cardio Debate about his recent study that investigates the differences in dual anti-platelet treatment for acute coronary syndrome in patients undergoing PCI or not. For more in-depth insight and analysis on issues in cardiology visit the Cardio Debate website: www.cardio-debate.com TRANSCRIPT Well this is a register-based nationwide study from Denmark. We wanted to look at the persistence with dual antiplatelet therapy in patients with acute coronary syndrome. We know that the guidelines recommended at least 12 months period of dual antiplatelet therapy for all patients after acute coronary syndrome. We have done a similar study in the early clodipogrel period, where we found that especially patients not undergoing revascularization, had no persistence on dual antiplatelet therapy, shorter treatment duration and less often started on therapy. Now we have three different ADP receptor blockers available – clopidogrel, prasugrel and ticagrelor. So what we did, we identified all patients admitted with acute coronary syndrome – that is myocardial infarction and unstable angina – and we included in total 9700 patients, mainly patients with myocardial infarction, 90 per cent (8700 patients), and 1100 patients with unstable angina. What we found, that patients not undergoing revascularization were less seldom started on dual antiplatelet therapy, especially among patients with unstable angina. And in total 30 per cent of patients were not started on dual antiplatelet therapy. When we looked at the persistence we found that approximately 30 per cent of patients stopped dual antiplatelet therapy after the first 60 days of treatment, especially among patients not undergoing revascularization. So the conclusion of the study is that we need to be more focused on using dual antiplatelet therapy, starting patients on treatment and improving persistence, especially among patients not undergoing revascularization. How will these findings impact on clinical practice? Well the impact is that this is a treatment that we know prevents recurrent vascular events. We need to focus on patients where they are more likely to start treatment. We also need to focus on the individuals that we are not starting on therapy, and identify the reasons among doctors and health care personnel why they are not starting treatment. And then to secure long-term treatment – at least for most patients 12 months of treatment – we now need to focus on those patients that are most likely to discontinue treatment prematurely.
Views: 136 Cardio Debate
Medical vocabulary: What does Amlodipine mean
 
00:12
What does Amlodipine mean in English?
Views: 47 botcaster inc. bot
define CALCIUM
 
02:47
Tulip is a female droid, at Your Service.
Views: 43 DROID STREAM
CPC: Hypertension and its complications in a young man with autoimmune disease
 
48:09
Hypertension and its complications in a young man with autoimmune disease. Presented by Dr. Eve Miller-Hodges and Dr. Neeraj Dhaun at Council on Hypertension 2016 Scientific Sessions in Orlando, Florida. Filmed 16 September 2016. AHA HYP16 Miller Hodges Dhaun 01
Views: 461 AHAScienceNews
What Is Calcium Scoring of the Heart? - Syed Bokhari, MD - Cardiology
 
00:22
Calcium scoring of the heart is diagnosed on a computerized axial tomography (CAT) scan of the heart. In this video, Syed Bokhari, MD, an interventional cardiologist at Riverside Community Hospital, says this doesn't correlate well to heart disease. Visit our website for more information: http://riversidecommunityhospital.com/.
Medical vocabulary: What does Ajmaline mean
 
00:19
What does Ajmaline mean in English?
Views: 164 botcaster inc. bot
A Case of Primary Aldosteronism With Discordant Hormonal and CT Findings
 
57:42
A real case presented by Dr. Laurence Amar at the 26th European Meeting on Hypertension and Cardiovascular Protection (ESH2016) as part of a Clinical-Pathological conference session sponsored by Hypertension, an American Heart Association journal. The case follows a 45 years-old man seen by his physician for headaches. He had a blood pressure of 190/110mmHg in both arms. The initial blood test revealed hypokalemia (plasma potassium of 3.1 mmol/l) with a normal plasma creatinine concentration (85 µmol/L), hyperglycemic tendency ( plasma glucose : 6.7 mmol/l) and normal lipid levels. ECG showed non specific diffuse ST changes, without QT prolongation or U waves. The patient was referred to the ESH Hypertension excellence center at Georges Pompidou hospital. Watch the video to hear experts discuss available options and lessons learned.
Views: 797 AHAScienceNews